Find coaches from Durham, NC, US to Greenville, SC

Next departures

Next departures from Durham to Greenville on 10 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Durham Greyhound Bus Station
    		1116 Woodruff RdCheapest
    Tornado Bus
      		Durham
      		Greenville, (SC - Taqueria Guadalajara #3)Fastest
      Wanda Coach
        		BP Gas Station
        		1111 Woodruff RoadNo tags
        Greyhound Lines, Inc.
          		Durham Greyhound Bus Station
          		1116 Woodruff RdNo tags
          FlixBus
            		Durham Greyhound Bus Station
            		1116 Woodruff RdNo tags

            Last refresh of the prices: Last Monday at 12:27 PM EST.

            Compare 2 ways to travel from Durham to Greenville

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 4 hours 45 minutes and with fares starting at just R 713, it presents an excellent value for a comfortable ride.

            9bus per day
            4h 45mAverage duration
            335 kmDistance
            8kgCO₂ emissions
            Bus
            		Average priceR 713 - R 2 706Average duration4h 45m
            8kg CO₂e
            Train
            		Average priceR 1 179 - R 1 876Average duration11h 20m
            31kg CO₂e

            Frequently asked questions about travelling from Durham, NC, US to Greenville, SC by bus

            1. How much does a bus ticket from Durham to Greenville cost?

              The bus ticket price from Durham to Greenville starts at R 713. The best way to find cheap bus tickets from Durham to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Durham to Greenville?

              The average travel time between Durham and Greenville is around 4h 45m, although the fastest bus will take about 4h 30m. This is the time it takes to travel the 342 km that separates the two cities.

            3. How many daily bus connections are there between Durham and Greenville?

              The number of buses from Durham to Greenville can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Durham to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Durham to Greenville?

              When taking the bus from Durham to Greenville, you can travel comfortably and safely with FlixBus, Wanda Coach, Tornado Bus.

            5. What are the departure and arrival stations when taking the bus from Durham to Greenville?

              Buses travelling between Durham and Greenville leave from Durham Greyhound Bus Station or Compare Foods Durham and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            07/11
            R 710
            08/11
            R 728
            Today
            No data
            10/11
            R 728
            11/11
            R 745
            12/11
            R 728
            13/11
            R 657
            14/11
            No data
            busbud logoThe cheapest trip from Durham, NC, US to Greenville, SC was searched and found on 13 Nov 2025 with a price of R 657

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Greenville, SC as early as possible.

            You can expect to pay from R 657 to R 2 572 for a bus ticket from Durham, NC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 657, which is on 2025-11-13.

            Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

            What's the cheapest way to go from Durham, NC, US to Greenville, SC?

            busbud logoThe bus is the cheapest travel choice for this destination

            Why choose Busbud?

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