Find coaches from Durham, NC, US to Charleston, SC, US

Previously seen journeys

Next departures from Durham to Charleston on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Durham Greyhound Bus Station
    		4565 Gaynor Ave, North CharlestonNo tags
    Greyhound
      		Durham Greyhound Bus Station
      		4565 Gaynor Ave, North CharlestonNo tags
      FlixBus + Greyhound
        		Durham Greyhound Bus Station
        		4565 Gaynor Ave, North CharlestonNo tags
        Greyhound + FlixBus
          		Durham Greyhound Bus Station
          		4565 Gaynor Ave, North CharlestonNo tags
          Greyhound + FlixBus
            		Durham Greyhound Bus Station
            		4565 Gaynor Ave, North CharlestonNo tags

            Accepted payments

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            • China Union Pay
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            Compare 2 ways to travel from Durham to Charleston

            We recommend taking the train

            Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 10 hours 3 minutes and with fares starting at just US$68, it presents an excellent value for a comfortable ride.

            1train per day
            10h 3mAverage duration
            362 kmDistance
            33kgCO₂ emissions
            Bus
            		Average priceUS$40 - US$145Average duration17h
            9kg CO₂e
            Train
            		Average priceUS$68 - US$157Average duration10h 3m
            33kg CO₂e

            Bus Durham, NC, US to Charleston, SC, US: Trip Overview

            Average ticket priceUS$58
            Average bus trip duration17h
            Number of daily buses1
            Earliest bus departure21:15
            Distance361 km
            Latest bus departure22:05

            Durham to Charleston Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Durham to Charleston.

            Bus service from Durham to Charleston will be provided by the most trusted bus companies.

            Whether it is cheap bus tickets or more luxurious buses going to Charleston from Durham, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions on the trip Durham, NC, US - Charleston, SC, US

            1. How much does a bus ticket from Durham to Charleston cost?

              The bus ticket price from Durham to Charleston starts at US$40. The best way to find cheap bus tickets from Durham to Charleston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Durham to Charleston?

              The average travel time between Durham and Charleston is around 17h, although the fastest bus will take about 16h 35m. This is the time it takes to travel the 370 km that separates the two cities.

            3. How many daily bus connections are there between Durham and Charleston?

              The number of buses from Durham to Charleston can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Durham to Charleston by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Durham to Charleston?

              When taking the bus from Durham to Charleston, you can travel comfortably and safely with FlixBus, Greyhound.

            5. What are the departure and arrival stations when taking the bus from Durham to Charleston?

              Buses travelling between Durham and Charleston leave from Durham Greyhound Bus Station or Compare Foods Durham and arrive at Charleston Bus Station.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            US$76
            01/11
            US$59
            Today
            No data
            03/11
            No data
            04/11
            No data
            05/11
            No data
            06/11
            US$57
            07/11
            US$61
            busbud logoThe cheapest trip from Durham, NC, US to Charleston, SC, US was searched and found on 06 Nov 2025 with a price of US$57

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Charleston, SC, US as early as possible.

            You can expect to pay from US$57 to US$76 for a bus ticket from Durham, NC, US to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$57, which is on 2025-11-06.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Durham to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.

            Much more than a mere vehicle taking you from Durham to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Charleston.

            Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Charleston while indulging in miles on end of beautiful scenic views.

            Did you know?

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            What's the cheapest way to go from Durham, NC, US to Charleston, SC, US?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Durham, NC, US by bus?

            Bus from Charleston, SC, US to Durham, NC, US

            You can also go to Charleston, SC, US by train

            Train from Durham, NC, US to Charleston, SC, US

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

            People from around the world trust Busbud

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