Find coaches from Des Moines to Charlotte, NC

Previously seen journeys

Next departures from Des Moines to Charlotte on 19 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
Des Moines (Subway)
Charlotte (Uptown)No tags
Greyhound + FlixBus
Bus
Des Moines (Subway)
Charlotte Bus StationNo tags
Greyhound + FlixBus
Bus
Des Moines (Subway)
Charlotte (Uptown)No tags
Greyhound + FlixBus
Bus
Des Moines (Subway)
Charlotte (Freedom Dr)No tags
FlixBus + Greyhound
Bus
Des Moines (Subway)
Charlotte Bus StationNo tags

Get from Des Moines to Charlotte

This route is served by bus only

The journey takes about 1 day, 8 hours 40 minutes, and with fares starting at just R 2 403, it presents an excellent value for a comfortable ride.

4bus per day
1d 8hAverage duration
1317 kmDistance
33kgCO₂ emissions

Frequently asked questions about travelling from Des Moines to Charlotte, NC by bus

  1. How much does a bus ticket from Des Moines to Charlotte cost?

    The bus ticket price from Des Moines to Charlotte starts at R 2 403. The best way to find cheap bus tickets from Des Moines to Charlotte is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Des Moines to Charlotte?

    The average travel time between Des Moines and Charlotte is around 1d 8h, although the fastest bus will take about 1d 4h. This is the time it takes to travel the 1319 km that separates the two cities.

  3. How many daily bus connections are there between Des Moines and Charlotte?

    The number of buses from Des Moines to Charlotte can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Des Moines to Charlotte by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Des Moines to Charlotte?

    When taking the bus from Des Moines to Charlotte, you can travel comfortably and safely with Greyhound.

  5. What are the departure and arrival stations when taking the bus from Des Moines to Charlotte?

    Buses travelling between Des Moines and Charlotte leave from Jefferson/Trailways Depot or 1514 East Grand Ave and arrive at Tornado & El Expreso Bus Company, Charlotte Douglas International Airport, Charlotte Greyhound Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
17/11
No data
18/11
R 2 277
Today
No data
20/11
No data
21/11
No data
22/11
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23/11
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24/11
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busbud logoThe cheapest trip from Des Moines to Charlotte, NC was searched and found on 18 Nov 2025 with a price of R 2 277

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Charlotte, NC as early as possible.

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