Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Charleston Bus Station | Downtown SD (Seaport) | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charleston Bus Station | UCSD Health La Jolla Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charleston Bus Station | San Diego (Old Town-FlixBus) | No tags | ||||
 | Bus | Charleston Bus Station | Greyhound Bus Stop | No tags |
Last refresh of the prices: Last Monday at 7:33 PM EST.
Compare 2 ways to travel from Charleston to San Diego
Among the sustainable travel choices, the Bus stands out as a good way to reach San Diego. The journey takes about 2 days, 11 hours 55 minutes and with fares starting at just R 3 814, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and San Diego?
Stops in Charleston
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 3 814
Frequently asked questions about travelling from Charleston, WV, US to San Diego, CA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Charleston to San Diego?
The cheapest bus tickets from Charleston to San Diego start at R 3 814. The average price for this route is around R 4 752. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Charleston to San Diego?
The average bus journey time from Charleston to San Diego is 2d 11h, covering a distance of 3256 km. The fastest bus gets you there in 2d 11h and is operated by Greyhound.
Which bus companies service the Charleston to San Diego route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Charleston to San Diego?
The earliest bus departs from Charleston to San Diego at 09:15. And the latest bus departs at 09:15.
What are the CO₂ emissions for the bus trip from Charleston to San Diego?
A bus trip from Charleston to San Diego produces an estimated 81 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, WV, US to San Diego, CA, US was searched and found on 15 Jan 2026 with a price of R 3 693To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to San Diego, CA, US as early as possible.
You can expect to pay from R 3 693 to R 5 281 for a bus ticket from Charleston, WV, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 693, which is on 2026-01-15.
What's the cheapest way to go from Charleston, WV, US to San Diego, CA, US?
The Bus is the cheapest travel choice for this destination
