Next departures from Buffalo to Chicago on 19 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
CheapestFastest
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
No tags
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Next departures from Buffalo to Chicago on 20 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
Cheapest
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
Fastest
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
No tags
Next departures from Buffalo to Chicago on 21 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
CheapestFastest
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
No tags
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Next departures from Buffalo to Chicago on 23 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
Cheapest
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
Fastest
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Last refresh of the prices: Today at 9:43 AM EST.
Compare 2 ways to travel from Buffalo to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 15 hours 30 minutes and with fares starting at just R 980, it presents an excellent value for a comfortable ride.
Based on 13 reviews, Greyhound was rated 2.4 stars for this trip. Greyhound ticket prices on this trip start at R 980, with the trip lasting on average 992.
Greyhound Buffalo Chicago recent customer reviews
Very unhappy with our travel from Buffalo to Chicago. The bus from buffalo to cleavelent was an hour late which was not the the biggest drama however the problem was that the greyhound bus station in both buffalo and cleavelend was very miserable, cold, dirty and smelly and most of all looking very unsafe. The whole experience really made us not want to travel with a bus anymore in our life.
1 out of 5 stars
Pamela D.
Before was good but yesterday i was shocked because i could not move back of my seat .most of the seat greyhound should fixed
2 out of 5 stars
Mostafa S.
I am dissatisfied with the services of Greyhound. Unsystematic and slow work.
Based on 11366 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 945
Frequently asked questions about travelling from Buffalo, NY to Chicago by bus
How much does a bus ticket from Buffalo to Chicago cost?
The bus ticket price from Buffalo to Chicago starts at R 980. The best way to find cheap bus tickets from Buffalo to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Buffalo to Chicago?
The average travel time between Buffalo and Chicago is around 15h 30m, although the fastest bus will take about 13h 10m. This is the time it takes to travel the 731 km that separates the two cities.
How many daily bus connections are there between Buffalo and Chicago?
The number of buses from Buffalo to Chicago can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Buffalo to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Buffalo to Chicago?
When taking the bus from Buffalo to Chicago, you can travel comfortably and safely with Greyhound, FlixBus.
What are the departure and arrival stations when taking the bus from Buffalo to Chicago?
Buses travelling between Buffalo and Chicago leave from Buffalo Airport or Transportation Center and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
16/11
R 2 041
17/11
R 1 654
Today
R 1 707
19/11
R 1 707
20/11
R 2 226
21/11
R 1 971
22/11
R 1 425
23/11
R 1 865
The cheapest trip from Buffalo, NY to Chicago was searched and found on 22 Nov 2025 with a price of R 1 425
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Chicago as early as possible.
You can expect to pay from R 1 425 to R 4 056 for a bus ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 425, which is on 2025-11-22.
What's the cheapest way to go from Buffalo, NY to Chicago?
The bus is the cheapest travel choice for this destination
The cheapest trip from Buffalo, NY to Chicago was searched and found on 22 Nov 2025 with a price of R 1 425
The bus is the cheapest travel choice for this destination
