Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Birmingham Greyhound Bus Station | 1116 Woodruff Rd | Cheapest | ||||
 | Bus | McDonald's - Birmingham | Greenville, (SC - Taqueria Guadalajara #3) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Birmingham Greyhound Bus Station | 1116 Woodruff Rd | No tags | ||||
| Bus | Birmingham Greyhound Bus Station | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Yesterday at 12:27 AM CST.
Compare 2 ways to travel from Birmingham to Greenville
Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 7 hours 54 minutes and with fares starting at just R 1 239, it presents an excellent value for a comfortable ride.
Where are the popular stops in Birmingham and Greenville?
Stops in Birmingham
- A
Birmingham Greyhound Bus Station
1801 Morris Ave, 35203 Birmingham, AL - B2427 Acton Rd, Vestavia Hills, AL 35243, USA
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling from Birmingham, US to Greenville, SC by bus
How much does a bus ticket from Birmingham to Greenville cost?
The bus ticket price from Birmingham to Greenville starts at R 796. The best way to find cheap bus tickets from Birmingham to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Birmingham to Greenville?
The average travel time between Birmingham and Greenville is around 7h 15m, although the fastest bus will take about 5h 35m. This is the time it takes to travel the 433 km that separates the two cities.
How many daily bus connections are there between Birmingham and Greenville?
The number of buses from Birmingham to Greenville can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Birmingham to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Birmingham to Greenville?
When taking the bus from Birmingham to Greenville, you can travel comfortably and safely with Greyhound, Tornado Bus, Amtrak.
What are the departure and arrival stations when taking the bus from Birmingham to Greenville?
Buses travelling between Birmingham and Greenville leave from Birmingham Greyhound Bus Station or McDonald's - Birmingham and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Birmingham, US to Greenville, SC was searched and found on 28 Nov 2025 with a price of R 1 104To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Birmingham, US to Greenville, SC as early as possible.
You can expect to pay from R 1 104 to R 3 028 for a bus ticket from Birmingham, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 104, which is on 2025-11-28.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Birmingham, US to Greenville, SC?
The bus is the cheapest travel choice for this destination
