Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Birmingham Greyhound Bus Station | 1116 Woodruff Rd | Cheapest | ||||
 | Bus | McDonald's - Birmingham | Greenville, (SC - Taqueria Guadalajara #3) | Fastest | ||||
 | Bus | Birmingham Greyhound Bus Station | 1116 Woodruff Rd | No tags | ||||
| Bus | Birmingham Greyhound Bus Station | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Today at 6:08 AM CST.
Compare 2 ways to travel from Birmingham to Greenville
Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 7 hours and with fares starting at just R 867, it presents an excellent value for a comfortable ride.
Where are the popular stops in Birmingham and Greenville?
Stops in Birmingham
- A
Birmingham Greyhound Bus Station
1801 Morris Ave, 35203 Birmingham, AL - B2427 Acton Rd, Vestavia Hills, AL 35243, USA
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling from Birmingham, US to Greenville, SC by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Birmingham to Greenville?
The cheapest bus tickets from Birmingham to Greenville start at R 867. The average price for this route is around R 1 275. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Birmingham to Greenville?
The average bus journey time from Birmingham to Greenville is 7h, covering a distance of 440 km. The fastest bus gets you there in 5h 35m and is operated by Tornado Bus.
Which bus companies service the Birmingham to Greenville route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, Tornado Bus, Amtrak.
What is the earliest and latest departure time for the bus from Birmingham to Greenville?
The earliest bus departs from Birmingham to Greenville at 02:25. And the latest bus departs at 22:40.
What are the CO₂ emissions for the bus trip from Birmingham to Greenville?
A bus trip from Birmingham to Greenville produces an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Birmingham to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5733 reviews.
Which bus company has the best Wi-Fi from Birmingham to Greenville?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.9.
Which bus company offers the most punctual service from Birmingham to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Birmingham to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Birmingham, US to Greenville, SC was searched and found on 31 Jan 2026 with a price of R 889To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Birmingham, US to Greenville, SC as early as possible.
You can expect to pay from R 889 to R 5 660 for a bus ticket from Birmingham, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 889, which is on 2026-01-31.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Birmingham, US to Greenville, SC?
The Bus is the cheapest travel choice for this destination
