Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Eurostar + SNCF | Train | Lyon Part Dieu Train Station | Brussels South/Midi Train Station | No tags | ||||
SNCF + Eurostar | Train | Lyon Part Dieu Train Station | Brussels South/Midi Train Station | No tags | ||||
Eurostar + SNCF | Train | Lyon Part Dieu Train Station | Brussels South/Midi Train Station | No tags | ||||
SNCF + Eurostar | Train | Lyon Part Dieu Train Station | Brussels South/Midi Train Station | No tags | ||||
Eurostar + SNCF | Train | Lyon Part Dieu Train Station | Brussels South/Midi Train Station | No tags |
Compare 3 ways to travel from Lyon to Brussels
Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 4 hours 13 minutes and with fares starting at just £53, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Lyon and Brussels?
Lyon
- AGare Part-Dieu - Vivier Merle, 69003 Lyon, France
- BRue de Esplanade, 69002 Lyon, France
Brussels
- ABoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- BRue de France 85, 1060 Saint-Gilles, Belgium
- C
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Train Companies
Based on 53 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the cleanliness and the temperature but often complained with the Wi-Fi. TGV inOui ticket prices on this trip start at £60
Frequently asked questions about travelling from Lyon to Brussels by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Lyon to Brussels?
The cheapest train tickets from Lyon to Brussels start from £53. The average price for this train route is around £123. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Lyon to Brussels?
The average train journey time from Lyon to Brussels is 4h 13m, covering a distance of 351 miles. The fastest train gets you there in 3h 44m and is operated by TGV inOui.
Which train operators serve the Lyon to Brussels route?
Several major train operators run on this route with 19 trains available per day.
What are the earliest and latest departure times for the train from Lyon to Brussels?
The earliest train from Lyon to Brussels departs at 05:50. And the latest train departs at 19:00.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lyon to Brussels was searched and found on 24 Dec 2025 with a price of £24To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Lyon to Brussels as early as possible.
You can expect to pay from £24 to £88 for a train ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £24, which is on 2025-12-24.
