Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Amtrak Station | Greenville Station | Cheapest | ||||
| Train | Amtrak Station | Greenville Station | Fastest | ||||
| Train | Amtrak Station | Greenville Station | No tags | ||||
| Train | Amtrak Station | Greenville Station | No tags | ||||
| Train | Amtrak Station | Greenville Station | No tags |
Last refresh of the prices: Today at 06:38 EST.
Compare 2 ways to travel from Detroit to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 3 hours 25 minutes and with fares starting at just £66, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5699 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at £318
Frequently asked questions about travelling from Detroit, MI to Greenville, SC by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Detroit to Greenville?
The cheapest train tickets from Detroit to Greenville start from £318. The average price for this train route is around £374. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Detroit to Greenville?
The average train journey time from Detroit to Greenville is 1d 19h, covering a distance of 519 miles. The fastest train gets you there in 1d 19h and is operated by Amtrak.
Which train operators serve the Detroit to Greenville route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Detroit to Greenville?
The earliest train from Detroit to Greenville departs at 09:35. And the latest train departs at 09:35.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Greenville, SC was searched and found on 6 Jan 2026 with a price of £213To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC as early as possible.
You can expect to pay from £213 to £1,062 for a train ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £213, which is on 2026-01-06.
