Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Sur | Penco | Cheapest | ||||
| Bus | Terminal Los Héroes | Penco | Fastest | ||||
| Bus | Terminal Sur | Penco | No tags | ||||
| Bus | Terminal Sur | Penco | No tags | ||||
| Bus | Terminal Sur | Penco | No tags |
Last refresh of the prices: 19/11/2025 -03.
Get from Santiago to Penco
The journey takes about 5 hours 6 minutes, and with fares starting at just £11, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago and Penco?
Stops in Santiago
- ATucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- BSantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- C
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Stops in Penco
- A
Terminal de Autobuses de Penco
Ruta 150 9, Penco, Región del Bío Bío, Chile
Compare bus companies
Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the Wi-Fi. Eme Bus ticket prices on this trip start at £11
Frequently asked questions about travelling by bus from Santiago, CL to Penco
How far is Penco from Santiago by coach?
The journey from Santiago to Penco by coach covers an approximate distance of 266 miles (429 km).
Is there a way to reach Penco from Santiago without flying?
To travel from Santiago to Penco without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to Penco was searched and found on 27 Nov 2025 with a price of £10To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Penco as early as possible.
You can expect to pay from £10 to £20 for a bus ticket from Santiago, CL to Penco based on the last 2 days. You can expect to find the cheapest price for the trip at £10, which is on 2025-11-27.
