Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santa Fe Speedway Gas Station | Cross Border Xpress CBX (USA) | CheapestFastest | ||||
| Bus | Santa Fe Speedway Gas Station | Cross Border Xpress CBX (USA) | No tags | ||||
| Bus | Santa Fe Speedway Gas Station | Cross Border Xpress CBX (USA) | No tags |
Last refresh of the prices: Yesterday at 19:46 MST.
Get from Santa Fe to San Diego
The journey takes about 1 day, 4 hours 25 minutes, and with fares starting at just £179, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Fe and San Diego?
Stops in Santa Fe
- ASanta Fe Amtrak Station, Santa Fe, NM 87501, USA
- BSanta Fe Amtrak Bus Stop, New Mexico 87506, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 268 reviews, the company was rated 3.3 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. Los Limousines ticket prices on this trip start at £179
Frequently asked questions about travelling by bus from Santa Fe, US to San Diego, CA, US
How far is San Diego from Santa Fe by coach?
The journey from Santa Fe to San Diego by coach covers an approximate distance of 672 miles (1084 km).
Is there a way to reach San Diego from Santa Fe without flying?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe, US to San Diego, CA, US was searched and found on 30 Nov 2025 with a price of £176To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, US to San Diego, CA, US as early as possible.
You can expect to pay from £176 to £176 for a bus ticket from Santa Fe, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £176, which is on 2025-11-30.
