Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santa Ana Regional Transportation Center | Cal Poly Vista Grande Dining Complex | No tags | ||||
| Bus | Santa Ana Regional Transportation Center | AMTRAK Station | No tags | ||||
| Bus | Santa Ana Regional Transportation Center | Cal Poly Vista Grande Dining Complex | No tags | ||||
| Bus | Santa Ana Regional Transportation Center | AMTRAK Station | No tags | ||||
| Bus | Santa Ana Regional Transportation Center | Cal Poly Vista Grande Dining Complex | No tags |
Compare 2 ways to travel from Santa Clara to San Luis Obispo
Among the sustainable travel choices, the train stands out as a good way to reach San Luis Obispo. The journey takes about 6 hours 51 minutes and with fares starting at just £38, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 5614 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at £59
Frequently asked questions about travelling by bus from Santa Clara, US to San Luis Obispo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Santa Clara to San Luis Obispo?
The cheapest coach tickets from Santa Clara to San Luis Obispo start from £59. The average price for this route is around £59. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Santa Clara to San Luis Obispo?
The average bus journey time from Santa Clara to San Luis Obispo is 10h 45m, covering a distance of 192 miles. The fastest bus can take you there in 10h 35m and is operated by Amtrak.
Which bus companies service the Santa Clara to San Luis Obispo route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Santa Clara to San Luis Obispo?
The earliest bus departs from Santa Clara to San Luis Obispo at 22:50. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Santa Clara to San Luis Obispo?
A bus journey from Santa Clara to San Luis Obispo produces an estimated 8 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Clara, US to San Luis Obispo was searched and found on 29 Nov 2025 with a price of £58To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Clara, US to San Luis Obispo as early as possible.
