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Bus Pisa to Frankfurt am Main: Trip Overview

Average ticket priceUS$130
Average bus trip duration19h 55m
Number of daily buses10
Earliest bus departure07:10
Distance448 miles
Latest bus departure23:30

Pisa to Frankfurt am Main Bus

Busbud helps you find a bus from Pisa to Frankfurt am Main. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Pisa to Frankfurt am Main will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Frankfurt am Main from Pisa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Pisa - Frankfurt am Main

  1. What's the distance between Pisa and Frankfurt am Main by coach?

    The journey from Pisa to Frankfurt am Main by coach covers an approximate distance of 450 miles (725 km).

  2. How can I travel from Pisa to Frankfurt am Main avoiding air travel?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
17/06
No data
18/06
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Today
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20/06
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21/06
US$67
22/06
US$121
23/06
No data
24/06
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busbud logoThe cheapest trip from Pisa to Frankfurt am Main was searched and found on 21 Jun 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Frankfurt am Main as early as possible.

You can expect to pay from US$67 to US$232 for a bus ticket from Pisa to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at US$67, which is on 2025-06-21.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Pisa and Frankfurt am Main!

Much more than a mere vehicle taking you from Pisa to Frankfurt am Main, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Pisa to Frankfurt am Main.

Tune out to the fine sounds of your best music playlist on your bus trip from Pisa to Frankfurt am Main while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Pisa by bus?

Bus from Pisa to Frankfurt am Main

You can also go to Frankfurt am Main by train

Train from Pisa to Frankfurt am Main

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