Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lampugnano | Brindisi Bus Stop | Cheapest | ||||
 | Bus | Milan Via Giuseppe Impastato | Brindisi Bus Stop | Fastest | ||||
| Bus | Milan Malpensa Airport T1, Bus station | Brindisi Bus Stop | No tags | ||||
| Bus | Lampugnano | Brindisi Bus Stop | No tags | ||||
| Bus | Lampugnano | Brindisi Bus Stop | No tags |
Last refresh of the prices: Last Thursday at 07:45 CET.
Compare 2 ways to travel from Milano to Brindisi
Among the sustainable travel choices, the carpool stands out as a good way to reach Brindisi. The journey takes about 11 hours and with fares starting at just £40, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£17 - £170 | Average duration17h 15m | 22kg CO₂e | ||
Carpool | Average price£40 - £67 | Average duration11h | 37kg CO₂e |
Where are the popular stops in Milano and Brindisi?
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- CPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Brindisi
- AVia Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy
- C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy - D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy - E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy - F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy
Compare bus companies
Frequently asked questions about travelling by bus from Milano to Brindisi
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Milano to Brindisi?
The cheapest coach tickets from Milano to Brindisi start from £17. The average price for this route is around £62. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Milano to Brindisi?
The average bus journey time from Milano to Brindisi is 17h 15m, covering a distance of 548 miles. The fastest bus can take you there in 12h 40m and is operated by MarinoBus.
Which bus companies service the Milano to Brindisi route?
What is the earliest and latest departure time for the bus from Milano to Brindisi?
The earliest bus departs from Milano to Brindisi at 00:30. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Milano to Brindisi?
A bus journey from Milano to Brindisi produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Milano to Brindisi?
According to Busbud customers, the highest-rated bus company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 893 reviews.
Which company has the best Wi-Fi from Milano to Brindisi?
Based on Busbud reviews, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.2.
Which bus company offers the most punctual service from Milano to Brindisi?
According to Busbud traveller reviews, the most punctual bus company on this route is MarinoBus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Milano to Brindisi?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Brindisi was searched and found on 2 Dec 2025 with a price of £15To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Brindisi as early as possible.
You can expect to pay from £15 to £139 for a bus ticket from Milano to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at £15, which is on 2025-12-02.
Usually MarinoBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
