Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Palermo | Lampugnano | Cheapest | ||||
| Bus | Terminal Bus Palermo | Milan San Donato Bus Station | Fastest | ||||
 | Bus | Terminal Bus Palermo | Milan (Malpensa Aeroporto Terminal 1) | No tags | ||||
| Bus | Terminal Bus Palermo | Milan (Malpensa Aeroporto Terminal 1) | No tags | ||||
| Bus | Terminal Bus Palermo | Aeroporto Malpensa T2 | No tags |
Last refresh of the prices: Today at 18:51 CET.
Compare 2 ways to travel from Palermo to Milano
Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 16 hours 50 minutes and with fares starting at just £80, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£40 - £196 | Average duration1d 1h | 22kg CO₂e | ||
Carpool | Average price£80 - £80 | Average duration16h 50m | 37kg CO₂e |
Where are the popular stops in Palermo and Milano?
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- BVia Giuseppe Impastato, 27, 20138 Milano, Italy
- DVia Giulio Natta, 228, 20151 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Frequently asked questions about travelling by bus from Palermo to Milano
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Palermo to Milano?
The cheapest coach tickets from Palermo to Milano start from £40. The average price for this route is around £90. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Palermo to Milano?
The average bus journey time from Palermo to Milano is 1d 1h, covering a distance of 549 miles. The fastest bus can take you there in 19h 10m and is operated by Autoservizi Salemi.
Which bus companies service the Palermo to Milano route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Autoservizi Salemi, Itabus, OneBus.
What is the earliest and latest departure time for the bus from Palermo to Milano?
The earliest bus departs from Palermo to Milano at 11:10. And the latest bus departs at 18:00.
What are the CO₂ emissions for the bus trip from Palermo to Milano?
A bus journey from Palermo to Milano produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Palermo to Milano?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 450 reviews.
Which company has the best Wi-Fi from Palermo to Milano?
Based on Busbud reviews, the bus company OneBus has the best Wi-Fi rating with a score of 5.0.
Which bus company offers the most punctual service from Palermo to Milano?
According to Busbud traveller reviews, the most punctual bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Palermo to Milano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Milano was searched and found on 30 Nov 2025 with a price of £75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Milano as early as possible.
You can expect to pay from £75 to £173 for a bus ticket from Palermo to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at £75, which is on 2025-11-30.
