Bus from La Crosse, WI to Milwaukee: Tickets & Timetables

Next bus departures

Next departures from La Crosse to Milwaukee on 28 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Jefferson LinesBus
    		La Crosse MTU Transit Center
    		St. Paul & N5thCheapest
    Jefferson LinesBus
      		632 17th Street North
      		St. Paul & N5thFastest
      Megabus USBus
        		La Crosse St Andrew St
        		Milwaukee Bus Station, St. Paul & N6th road.No tags
        Megabus USBus
          		La Crosse WI - University of Wisconsin (LSW)
          		Milwaukee Bus Station, St. Paul & N6th road.No tags

          Last refresh of the prices: Yesterday at 23:27 CST.

          Compare 2 ways to travel from La Crosse to Milwaukee

          We recommend taking the train

          Among the sustainable travel choices, the train stands out as a good way to reach Milwaukee. The journey takes about 3 hours 36 minutes and with fares starting at just £21, it presents an excellent value for a comfortable ride.

          4train per day
          3h 36mAverage duration
          178 milesDistance
          26kgCO₂ emissions
          Bus
          		Average price£32 - £44Average duration4h 40m
          7kg CO₂e
          Train
          		Average price£21 - £99Average duration3h 36m
          26kg CO₂e

          Frequently asked questions about travelling by bus from La Crosse, WI to Milwaukee

          Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

          1. How much is the bus ticket from La Crosse to Milwaukee?

            The cheapest coach tickets from La Crosse to Milwaukee start from £32. The average price for this route is around £35. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

          2. How long is the bus journey from La Crosse to Milwaukee?

            The average bus journey time from La Crosse to Milwaukee is 4h 40m, covering a distance of 175 miles. The fastest bus can take you there in 3h 45m and is operated by Jefferson Lines.

          3. Which bus companies service the La Crosse to Milwaukee route?

            Several major bus companies operate on this route with 3 buses available per day, including services from Megabus, Jefferson Lines, Amtrak.

          4. What is the earliest and latest departure time for the bus from La Crosse to Milwaukee?

            The earliest bus departs from La Crosse to Milwaukee at 14:30. And the latest bus departs at 16:10.

          5. What are the CO₂ emissions for the bus trip from La Crosse to Milwaukee?

            A bus journey from La Crosse to Milwaukee produces an estimated 7 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

          6. Which is the best bus company from La Crosse to Milwaukee?

            According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.

          7. Which company has the best Wi-Fi from La Crosse to Milwaukee?

            Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

          8. Which bus company offers the most punctual service from La Crosse to Milwaukee?

            According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.

          9. Which bus company has the cleanest buses from La Crosse to Milwaukee?

            According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          25/11
          £34
          26/11
          £34
          Today
          £31
          28/11
          £34
          29/11
          £34
          30/11
          £34
          01/12
          £34
          02/12
          £34
          busbud logoThe cheapest trip from La Crosse, WI to Milwaukee was searched and found on 27 Nov 2025 with a price of £31

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Milwaukee as early as possible.

          You can expect to pay from £31 to £42 for a bus ticket from La Crosse, WI to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at £34, which is on 2025-11-28.

          What's the cheapest way to go from La Crosse, WI to Milwaukee?

          busbud logoThe bus is the cheapest travel choice for this destination

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