How far is Chicago from Jefferson City by coach?

The journey from Jefferson City to Chicago by coach covers an approximate distance of 329 miles (531 km).

Is there a way to reach Chicago from Jefferson City without flying?

You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Bus Jefferson City to Chicago from £45 | Refundable Tickets

Next bus departures

Next departures from Jefferson City to Chicago on 24 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	Fastest
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 25 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 26 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 27 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 28 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 29 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 30 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Next departures from Jefferson City to Chicago on 1 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 5m	05:20	Chicago 95Th & Dan Ryan	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	19:15	Jefferson City	10h 30m	05:45	Downtown Greyhound Station	No tags
	Bus	19:15	Jefferson City	18h 55m	14:10	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Today at 00:21 CST.

Compare 2 ways to travel from Jefferson City to Chicago

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 8 hours 11 minutes and with fares starting at just £39, it presents an excellent value for a comfortable ride.

2train per day

8h 11mAverage duration

330 milesDistance

48kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£43 - £121	Average duration10h 30m	CO₂ emissions 13kg CO₂e
Train	Average price£39 - £115	Average duration8h 11m	CO₂ emissions 48kg CO₂e

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £44

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling by bus from Jefferson City, MO to Chicago

How far is Chicago from Jefferson City by coach?
The journey from Jefferson City to Chicago by coach covers an approximate distance of 329 miles (531 km).
Is there a way to reach Chicago from Jefferson City without flying?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

22/11

£100

23/11

£105

Today

£152

25/11

£159

26/11

£95

27/11

£92

28/11

£144

29/11

£121

The cheapest trip from Jefferson City, MO to Chicago was searched and found on 27 Nov 2025 with a price of £92

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jefferson City, MO to Chicago as early as possible.

You can expect to pay from £92 to £159 for a bus ticket from Jefferson City, MO to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £92, which is on 2025-11-27.