How far is Florence from Jacksonville by coach?

The distance between Jacksonville and Florence by coach is approximately 293 miles (472 km).

What is the best way to go from Jacksonville to Florence without flying?

You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Bus Jacksonville to Florence from £34 | Refundable Tickets

Next bus departures

Next departures from Jacksonville to Florence on 13 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	08:25	Jacksonville Bus Station	5h 10m	13:35	Bus station	CheapestFastest
	Bus	18:30	Jacksonville Bus Station	5h 35m	00:05	Florence, SC	No tags

Last refresh of the prices: Today at 11:59 EST.

Compare 2 ways to travel from Jacksonville to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 7 hours and with fares starting at just £37, it presents an excellent value for a comfortable ride.

2bus per day

7hAverage duration

289 milesDistance

12kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£37 - £77	Average duration7h	CO₂ emissions 12kg CO₂e
Train	Average price£41 - £91	Average duration6h 11m	CO₂ emissions 42kg CO₂e

Compare bus companies

FlixBus

3.5/511,290 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

Greyhound

3.5/587,370 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Jacksonville and Florence?

Stops in Jacksonville

A - Jacksonville Amtrak Station

B - W Forsyth St

C - Kings Avenue Station

D - JRTC Greyhound Bus Station

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions about travelling by bus from Jacksonville, FL to Florence, SC, US

How far is Florence from Jacksonville by coach?
The distance between Jacksonville and Florence by coach is approximately 293 miles (472 km).
What is the best way to go from Jacksonville to Florence without flying?
You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/11

£46

11/11

No data

Today

£50

13/11

£51

14/11

£34

15/11

£40

16/11

£37

17/11

£37

The cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on 14 Nov 2025 with a price of £34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Florence, SC, US as early as possible.

You can expect to pay from £34 to £55 for a bus ticket from Jacksonville, FL to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £34, which is on 2025-11-14.