Find coaches from Jacksonville, FL to Florence, SC, US

Previously seen journeys

Next departures from Jacksonville to Florence on 7 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Jacksonville Bus Station
    		Bus stationNo tags
    FlixBus
      		Jacksonville Bus Station
      		Florence, SCNo tags
      Greyhound
        		Jacksonville Bus Station
        		Bus stationNo tags
        FlixBus
          		Jacksonville Bus Station
          		Florence, SCNo tags
          Greyhound
            		Jacksonville Bus Station
            		Bus stationNo tags

            Compare 2 ways to travel from Jacksonville to Florence

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 7 hours and with fares starting at just £37, it presents an excellent value for a comfortable ride.

            2bus per day
            7hAverage duration
            289 milesDistance
            12kgCO₂ emissions
            Bus
            		Average price£37 - £77Average duration7h
            12kg CO₂e
            Train
            		Average price£41 - £91Average duration6h 11m
            42kg CO₂e

            Frequently asked questions about travelling by bus from Jacksonville, FL to Florence, SC, US

            1. How far is Florence from Jacksonville by coach?

              The distance between Jacksonville and Florence by coach is approximately 293 miles (472 km).

            2. What is the best way to go from Jacksonville to Florence without flying?

              You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            05/11
            No data
            06/11
            £40
            Today
            No data
            08/11
            £34
            09/11
            No data
            10/11
            No data
            11/11
            No data
            12/11
            £36
            busbud logoThe cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on 8 Nov 2025 with a price of £34

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Florence, SC, US as early as possible.

            You can expect to pay from £34 to £55 for a bus ticket from Jacksonville, FL to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £34, which is on 2025-11-08.

            What's the cheapest way to go from Jacksonville, FL to Florence, SC, US?

            busbud logoThe bus is the cheapest travel choice for this destination

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

            People from around the world trust Busbud

            ‌

            Popular Buses Connecting Jacksonville

            Buses Leaving from Jacksonville

            Buses Going to Jacksonville

            Popular Buses Connecting Florence

            Buses Leaving from Florence

            Buses Going to Florence