Find coaches from Jacksonville, FL to Florence, SC, US

Next bus departures

Next departures from Jacksonville to Florence on 12 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Jacksonville Bus Station
Bus stationCheapestFastest

Last refresh of the prices: Today at 04:13 EST.

Compare 2 ways to travel from Jacksonville to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 7 hours and with fares starting at just £37, it presents an excellent value for a comfortable ride.

2bus per day
7hAverage duration
289 milesDistance
12kgCO₂ emissions
Bus
Average price£37 - £77Average duration7h
12kg CO₂e
Train
Average price£41 - £91Average duration6h 11m
42kg CO₂e

Frequently asked questions about travelling by bus from Jacksonville, FL to Florence, SC, US

  1. How far is Florence from Jacksonville by coach?

    The distance between Jacksonville and Florence by coach is approximately 293 miles (472 km).

  2. What is the best way to go from Jacksonville to Florence without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
£46
10/11
£46
Today
No data
12/11
£50
13/11
No data
14/11
£34
15/11
£40
16/11
£37
busbud logoThe cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on 14 Nov 2025 with a price of £34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Florence, SC, US as early as possible.

You can expect to pay from £34 to £55 for a bus ticket from Jacksonville, FL to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £34, which is on 2025-11-14.

What's the cheapest way to go from Jacksonville, FL to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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