Train from Frankfurt am Main to Prague: Tickets & Schedules

Next train departures

Next departures for Frankfurt am Main to Prague on December 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Deutsche Bahn ICE + EuroCity Train
Train
Frankfurt Süd
Hlavní nádražíCheapest
Deutsche Bahn ICE + InterCity + EuroCity Train
Train
Frankfurt Süd
Hlavní nádražíFastest
Deutsche Bahn ICE + EuroCity Train
Train
Frankfurt Süd
Hlavní nádražíNo tags
Deutsche Bahn ICE + InterCity + EuroCity Train
Train
Frankfurt Süd
Hlavní nádražíNo tags
Deutsche Bahn ICE + EuroCity Train
Train
Frankfurt Süd
Hlavní nádražíNo tags

Last refresh of the prices: Yesterday at 11:55 PM CET.

Compare 3 ways to go from Frankfurt am Main to Prague

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 20 minutes, and with fares starting at just $41, it presents an excellent value for a comfortable ride.

2carpool per day
5h 20mAverage Duration
410 kmDistance
17kgCO₂ emissions
Bus
Average Price$23 - $147Average Duration8h 56m
10kg CO₂e
Train
Average Price$45 - $362Average Duration7h 47m
10kg CO₂e
Carpool
Average Price$41 - $82Average Duration5h 20m
17kg CO₂e

Frequently asked questions about travelling from Frankfurt am Main to Prague by train

  1. How much does a cheap train ticket from Frankfurt am Main to Prague cost?

    The average train ticket price from Frankfurt am Main to Prague is $162. The best way to find cheap train tickets from Frankfurt am Main to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from Frankfurt am Main to Prague?

    A train trip between Frankfurt am Main and Prague is around 7h 47m, although the fastest train will take about 7h 1m. This is the time it takes to travel the 410 km that separates the two cities.

  3. How many daily trains are there between Frankfurt am Main and Prague?

    The number of trains from Frankfurt am Main to Prague can differ depending on the day of the week. On average, there are 33. Some trains are direct while others include transferring trains. Simplify your train trip from Frankfurt am Main to Prague by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from Frankfurt am Main to Prague?

    When taking the train from Frankfurt am Main to Prague, you can travel comfortably and safely with Deutsche Bahn.

  5. What are the departure and arrival stations for a train from Frankfurt am Main to Prague?

    Trains travelling between Frankfurt am Main and Prague leave from Südbahnhof or Frankfurt Airport and arrive at Hlavní nádraží, Florenc, PRG Airport.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-28
$111
11-29
No data
Today
No data
12-01
No data
12-02
No data
12-03
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12-04
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12-05
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busbud logoThe cheapest trip from Frankfurt am Main to Prague was searched and found on Nov 28, 2025 with a price of $111

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Frankfurt am Main to Prague, as early as possible.

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