How much is the bus ticket from Syracuse to Chicago?

The cheapest bus tickets from Syracuse to Chicago start from $104. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Syracuse to Chicago?

The average bus travel time from Syracuse to Chicago is 1d 5h, covering a distance of 952 km. The quickest bus can get you there in 16h 35m and is operated by Greyhound .

Which bus companies service the Syracuse to Chicago route?

Several major bus companies operate on this route with 10 buses available per day, including services from Greyhound , FlixBus , New York Trailways , Adirondack Trailways .

What are the earliest and latest departure times for the bus from Syracuse to Chicago?

The earliest bus departs from Syracuse to Chicago at 3:35am. And the latest bus departs at 9:00pm.

What are the CO₂ emissions for the bus trip from Syracuse to Chicago?

A bus trip from Syracuse to Chicago generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Syracuse to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways , with an average rating of 4.1 out of 5 stars based on 1142 reviews.

Which bus company has the best Wi-Fi from Syracuse to Chicago?

Based on Busbud reviews, the bus company New York Trailways has the highest Wi-Fi rating with a score of 3.1.

Which bus company has the best on-time performance from Syracuse to Chicago?

According to Busbud traveller reviews, the most punctual bus company on this route is Adirondack Trailways , with a punctuality rating of 4.3 out of 5 stars.

Which bus company has the cleanest buses from Syracuse to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways , with a cleanliness rating of 4.7 out of 5 stars.

Bus Syracuse to Chicago from $101 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Chicago on January 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	1d 17h	1:25pm	Chicago 95Th & Dan Ryan	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	1d 14h	10:00am	Downtown Greyhound Station	Fastest

Next departures for Syracuse to Chicago on January 9
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	1d 7h	8:05pm	Downtown Greyhound Station	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 5h	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for Syracuse to Chicago on January 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	1d 7h	8:05pm	Downtown Greyhound Station	No tags
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 5h	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for Syracuse to Chicago on January 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30am	Syracuse (Regional Transportation Center)	20h 5m	11:35pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:00pm	Syracuse (Regional Transportation Center)	1d 2h	8:05pm	Downtown Greyhound Station	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Syracuse to Chicago on January 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30am	Syracuse (Regional Transportation Center)	20h 5m	11:35pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	1d 7h	8:05pm	Downtown Greyhound Station	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Syracuse to Chicago on January 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	1d 10h	11:00pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	1d 7h	8:05pm	Downtown Greyhound Station	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Syracuse to Chicago on January 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30am	Syracuse (Regional Transportation Center)	20h 5m	11:35pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 5h	1:25pm	Chicago 95Th & Dan Ryan	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Syracuse to Chicago on January 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30am	Syracuse (Regional Transportation Center)	20h 5m	11:35pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:30am	Syracuse (Regional Transportation Center)	16h 35m	8:05pm	Downtown Greyhound Station	Fastest
	Bus	9:25am	Syracuse (Regional Transportation Center)	1d 1h	10:00am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	Syracuse (Regional Transportation Center)	1d 7h	8:05pm	Downtown Greyhound Station	No tags
	Bus	4:30am	Syracuse (Regional Transportation Center)	1d 4h	8:00am	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Today at 10:52 AM EST.

Compare 2 ways to go from Syracuse to Chicago

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 13 hours 7 minutes, and with fares starting at just $85, it presents an excellent value for a comfortable ride.

1train per day

13h 7mAverage Duration

950 kmDistance

86kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$104 - $482	Average Duration1d 5h	CO₂ emissions 24kg CO₂e
Train	Average Price$85 - $305	Average Duration13h 7m	CO₂ emissions 86kg CO₂e

Where are the popular stops in Syracuse and Chicago?

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587,492 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,965 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

New York Trailways

4/54,431 reviews

Staff4.6

Timeliness4.1

Cleanliness4.5

Wifi3.2

Adirondack Trailways

4/51,144 reviews

Staff4.6

Timeliness4.3

Cleanliness4.7

Wifi2.3

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Syracuse, US to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Syracuse to Chicago?
The cheapest bus tickets from Syracuse to Chicago start from $104. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Chicago?
The average bus travel time from Syracuse to Chicago is 1d 5h, covering a distance of 952 km. The quickest bus can get you there in 16h 35m and is operated by Greyhound.
Which bus companies service the Syracuse to Chicago route?
Several major bus companies operate on this route with 10 buses available per day, including services from Greyhound, FlixBus, New York Trailways, Adirondack Trailways.
What are the earliest and latest departure times for the bus from Syracuse to Chicago?
The earliest bus departs from Syracuse to Chicago at 3:35am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Chicago?
A bus trip from Syracuse to Chicago generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways, with an average rating of 4.1 out of 5 stars based on 1142 reviews.
Which bus company has the best Wi-Fi from Syracuse to Chicago?
Based on Busbud reviews, the bus company New York Trailways has the highest Wi-Fi rating with a score of 3.1.
Which bus company has the best on-time performance from Syracuse to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is Adirondack Trailways, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-06

$182

01-07

$174

Today

$182

01-09

$172

01-10

$176

01-11

$181

01-12

$154

01-13

$160

The cheapest trip from Syracuse, US to Chicago was searched and found on Jan 12, 2026 with a price of $154

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Chicago, as early as possible.

You can expect to pay from $154 to $299 for a bus ticket from Syracuse, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $154 which is on 2026-01-12.