Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | 199 Spring Garden St. | CheapestFastest | ||||
| Bus | Gateway Station | 199 Spring Garden St. | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | 199 Spring Garden St. | No tags | ||||
 | Bus | Gateway Station | Philadelphia, 199 Spring Garden St | No tags | ||||
| Bus | Gateway Station | 199 Spring Garden St. | No tags |
Last refresh of the prices: Last Sunday at 9:22 PM CST.
Compare 2 ways to go from St. Louis to Philadelphia
Among the sustainable travel choices, the bus stands out as a good way to reach Philadelphia. The journey takes about 1 day, 8 hours 15 minutes, and with fares starting at just $131, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Philadelphia?
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
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Frequently asked questions about travelling from St. Louis to Philadelphia, PA by bus
What is the travel distance from St. Louis to Philadelphia?
The distance between St. Louis and Philadelphia is approximately 1303 km (808 miles).
What are the departure and arrival locations for buses traveling from St. Louis to Philadelphia?
Buses departing from Gateway Station in St. Louis will take you to Philadelphia Airport in Philadelphia.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Philadelphia, PA was searched and found on Nov 24, 2025 with a price of $174To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Philadelphia, PA, as early as possible.
You can expect to pay from $174 to $407 for a bus ticket from St. Louis to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $174 which is on 2025-11-27.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from St. Louis to Philadelphia, PA?
The bus is the cheapest travel choice for this destination
