Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Detroit Bus Station | CheapestFastest | ||||
 | Bus | Gateway Station | Detroit Bus Station | No tags |
Last refresh of the prices: Yesterday at 8:46 AM CST.
Compare 2 ways to go from St. Louis to Detroit
Among the sustainable travel choices, the bus stands out as a good way to reach Detroit. The journey takes about 15 hours 15 minutes, and with fares starting at just $94, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Detroit?
Compare bus companies
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $94
Frequently asked questions about travelling from St. Louis to Detroit, MI by bus
What is the travel distance from St. Louis to Detroit?
The distance between St. Louis and Detroit is approximately 733 km (454 miles).
What are the departure and arrival locations for buses traveling from St. Louis to Detroit?
Buses departing from Gateway Station in St. Louis will take you to Detroit Bus Station in Detroit.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Detroit, MI was searched and found on Nov 27, 2025 with a price of $120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Detroit, MI, as early as possible.
You can expect to pay from $120 to $257 for a bus ticket from St. Louis to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-11-27.
What's the cheapest way to go from St. Louis to Detroit, MI?
The bus is the cheapest travel choice for this destination
