Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Barra Funda - Sao Paulo | Santa Cruz de la Sierra | CheapestFastest |
Last refresh of the prices: Last Wednesday at 12:12 PM -03.
Get from São Paulo to Santa Cruz de la Sierra
The journey takes about 1 day, 15 hours 30 minutes, and with fares starting at just $254, it presents an excellent value for a comfortable ride.
Where are the popular stops in São Paulo and Santa Cruz de la Sierra?
Stops in São Paulo
- ATerminal Rodoviário da Barra Funda, Avenida Auro Soares de Moura Andrade, 664 - Barra Funda, São Paulo - SP, 01156-001, Brazil
- CTerminal Intermunicipal do Jabaquara, Rua dos Jequitibás, 80 - Jabaquara, São Paulo - SP, 04321-090
- D
Praça do Patriarca
Praça do Patriarca 78, Centro, São Paulo - SP, Brazil - E
São Paulo
São Paulo - F
Tietê
Terminal Rodoviário do Tietê, Avenida Cruzeiro do Sul, , 1800 Santana , 02030-000 São Paulo, SP
Stops in Santa Cruz de la Sierra
- AAv Intermodal, Santa Cruz de la Sierra, Bolivia
Compare bus companies
Based on 20 reviews, La Preferida Bus was rated 2.2 stars for this trip. La Preferida Bus ticket prices on this trip start at $254, with the trip lasting on average 2370.
La Preferida Bus São Paulo Santa Cruz de la Sierra recent customer reviews
Hi . When I cross the Border at the terminal in Bolivia was no body to tell me at what time was the bus to Santa Cruz , because the lady she went to a clinic so I buy another ticket to Santa Cruz .
Pier Luigi C.
Frequently asked questions about travelling from São Paulo to Santa Cruz de la Sierra, BO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from São Paulo to Santa Cruz de la Sierra?
The cheapest bus tickets from São Paulo to Santa Cruz de la Sierra start from $254. The average price for this route is around $399. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from São Paulo to Santa Cruz de la Sierra?
The average bus travel time from São Paulo to Santa Cruz de la Sierra is 1d 15h, covering a distance of 1830 km. The quickest bus can get you there in 1d 15h and is operated by La Preferida Bus.
Which bus companies service the São Paulo to Santa Cruz de la Sierra route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from São Paulo to Santa Cruz de la Sierra?
The earliest bus departs from São Paulo to Santa Cruz de la Sierra at 1:00pm. And the latest bus departs at 1:00pm.
What are the CO₂ emissions for the bus trip from São Paulo to Santa Cruz de la Sierra?
A bus trip from São Paulo to Santa Cruz de la Sierra generates an estimated 46 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from São Paulo to Santa Cruz de la Sierra, BO was searched and found on Nov 26, 2025 with a price of $242To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from São Paulo to Santa Cruz de la Sierra, BO, as early as possible.
You can expect to pay from $242 to $425 for a bus ticket from São Paulo to Santa Cruz de la Sierra, BO based on the last 2 days. You can expect to find the cheapest price for the trip at $242 which is on 2025-11-29.
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