Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santo Tome - El Paso | Terminal de Retiro | CheapestFastest | ||||
 | Bus | Santo Tome - El Paso | Terminal de Retiro | No tags | ||||
| Bus | Santo Tome - El Paso | Terminal de Retiro | No tags | ||||
 | Bus | Santo Tome - El Paso | Terminal de Retiro | No tags | ||||
 | Bus | Santo Tome - El Paso | Terminal de Retiro | No tags |
Last refresh of the prices: Last Thursday at 5:12 PM -03.
Get from Santo Tomé to Buenos Aires
The journey takes about 6 hours, and with fares starting at just $28, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santo Tomé and Buenos Aires?
Stops in Santo Tomé
- A
Terminal de Santo Tomé
Avellaneda 2000, S3016ADJ Santo Tome, Santa Fe, Argentina
Stops in Buenos Aires
- ATerminal de Ómnibus de Buenos Aires, Av. Antártida y Calle 10. Argentina, Calle 10 &, CABA, Argentina
- BAeroparque Jorge Newbery
- CAv. Hipólito Yrigoyen 4600, B1824ABO Lanús Oeste, Cdad. Autónoma de Buenos Aires, Argentina
- DL. Caputo, Remedios de Escalada, Buenos Aires, Argentina
- E
Terminal Puente La Noria
Corrientes 434, B1832ELJ Lomas de Zamora, Buenos Aires, Argentina - F
Parada de Autobus Valentin Alsina
Itapiru 831, B1822DIN Valentín Alsina, Buenos Aires, Argentina
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Frequently asked questions about travelling from Santo Tomé, Santa Fe, AR to Buenos Aires, AR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santo Tomé to Buenos Aires?
The cheapest bus tickets from Santo Tomé to Buenos Aires start from $28. The average price for this route is around $45. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santo Tomé to Buenos Aires?
The average bus travel time from Santo Tomé to Buenos Aires is 6h, covering a distance of 394 km. The quickest bus can get you there in 5h 15m and is operated by Zenit.
Which bus companies service the Santo Tomé to Buenos Aires route?
Several major bus companies operate on this route with 5 buses available per day, including services from Costera Criolla, Flechabus, Zenit, Rápido Tata.
What are the earliest and latest departure times for the bus from Santo Tomé to Buenos Aires?
The earliest bus departs from Santo Tomé to Buenos Aires at 12:10am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Santo Tomé to Buenos Aires?
A bus trip from Santo Tomé to Buenos Aires generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Santo Tomé to Buenos Aires?
According to Busbud customers, the highest-rated bus company on this route is Zenit, with an average rating of 4.1 out of 5 stars based on 347 reviews.
Which bus company has the best Wi-Fi from Santo Tomé to Buenos Aires?
Based on Busbud reviews, the bus company Zenit has the highest Wi-Fi rating with a score of 2.5.
Which bus company has the best on-time performance from Santo Tomé to Buenos Aires?
According to Busbud traveller reviews, the most punctual bus company on this route is Zenit, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Santo Tomé to Buenos Aires?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Costera Criolla, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santo Tomé, Santa Fe, AR to Buenos Aires, AR was searched and found on Nov 30, 2025 with a price of $37To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santo Tomé, Santa Fe, AR to Buenos Aires, AR, as early as possible.
You can expect to pay from $37 to $65 for a bus ticket from Santo Tomé, Santa Fe, AR to Buenos Aires, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-11-30.
Usually Flechabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
