Bus from Santa Ana, US to Guadalajara, MX: Tickets & Schedules

Previously seen trips

Next departures for Santa Ana to Guadalajara on January 7
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ACN AutobusesBus
Santana C.A - Stop
Terminal ZapopanNo tags
ACN AutobusesBus
Santana C.A - Stop
Nueva CentralNo tags
ACN AutobusesBus
Santana C.A - Stop
Plaza Santa Alicia, ZapopanNo tags
ACN AutobusesBus
Santana C.A - Stop
Nueva CentralNo tags
ACN AutobusesBus
Santana C.A - Stop
Plaza Santa Alicia, ZapopanNo tags

Get from Santa Ana to Guadalajara

This route is served by bus only

The journey takes about 1 day, 4 hours 40 minutes, and with fares starting at just $406, it presents an excellent value for a comfortable ride.

3bus per day
1d 4hAverage Duration
2033 kmDistance
51kgCO₂ emissions

Frequently asked questions about travelling from Santa Ana, US to Guadalajara, MX by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Santa Ana to Guadalajara?

    The cheapest bus tickets from Santa Ana to Guadalajara start from $406. The average price for this route is around $406. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Santa Ana to Guadalajara?

    The average bus travel time from Santa Ana to Guadalajara is 1d 4h, covering a distance of 2033 km. The quickest bus can get you there in 22h 59m and is operated by Autotravel.

  3. Which bus companies service the Santa Ana to Guadalajara route?

    Several major bus companies operate on this route with 3 buses available per day, including services from ACN Autobuses, Autotravel.

  4. What are the earliest and latest departure times for the bus from Santa Ana to Guadalajara?

    The earliest bus departs from Santa Ana to Guadalajara at 8:10pm. And the latest bus departs at 8:40pm.

  5. What are the CO₂ emissions for the bus trip from Santa Ana to Guadalajara?

    A bus trip from Santa Ana to Guadalajara generates an estimated 51 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Santa Ana to Guadalajara?

    According to Busbud customers, the highest-rated bus company on this route is ACN Autobuses, with an average rating of 2.3 out of 5 stars based on 143 reviews.

  7. Which bus company has the best Wi-Fi from Santa Ana to Guadalajara?

    Based on Busbud reviews, the bus company ACN Autobuses has the highest Wi-Fi rating with a score of 1.9.

  8. Which bus company has the best on-time performance from Santa Ana to Guadalajara?

    According to Busbud traveller reviews, the most punctual bus company on this route is ACN Autobuses, with a punctuality rating of 2.1 out of 5 stars.

  9. Which bus company has the cleanest buses from Santa Ana to Guadalajara?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ACN Autobuses, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01-05
$406
01-06
$406
Today
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busbud logoThe cheapest trip from Santa Ana, US to Guadalajara, MX was searched and found on Jan 5, 2026 with a price of $406

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Guadalajara, MX, as early as possible.

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