Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | San Ysidro Greyhound Bus Station | 1157 F St | Cheapest | ||||
 | Bus | Mc. Donald´s (San Ysidro Border Crossing) | E St | Fastest | ||||
| Bus | Mc. Donald´s (San Ysidro Border Crossing) | E St | No tags | ||||
 | Bus | San Ysidro Bus terminal | Amtrak Station | No tags | ||||
 | Bus | San Ysidro Bus terminal | Amtrak Station | No tags |
Last refresh of the prices: Today at 9:30 AM PST.
Get from San Ysidro to Fresno
The journey takes about 9 hours 20 minutes, and with fares starting at just $73, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Ysidro and Fresno?
Stops in Fresno
- A2660 Tulare St, Fresno, CA 93721, USA
- B919 E St, Fresno, CA 93706, USA
- C1157 F St, Fresno, CA 93706 , USA
- D
Train / Greyhound Station
1033 H St, Fresno, CA 93721 - E
W Shaw Ave
Carl's Jr., 5275 W Shaw Ave, Fresno, CA 93722, USA
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Frequently asked questions about travelling from San Ysidro, CA to Fresno, US by bus
How far is San Ysidro from Fresno?
It's about 529 km (328 miles) from San Ysidro to Fresno.
What are the departure and arrival locations for buses traveling from San Ysidro to Fresno?
Buses traveling this route start their trip at San Ysidro Greyhound Bus Station, in San Ysidro, and end it at Amtrak Station, in Fresno.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Ysidro, CA to Fresno, US was searched and found on Nov 29, 2025 with a price of $80To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Fresno, US, as early as possible.
You can expect to pay from $80 to $247 for a bus ticket from San Ysidro, CA to Fresno, US based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2025-11-29.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
