Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | No tags |
Last refresh of the prices: Last Wednesday at 11:07 PM EST.
Compare 2 ways to go from Salisbury to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 23 hours 5 minutes, and with fares starting at just $179, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and St. Louis?
Compare bus companies
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $189
Frequently asked questions about travelling from Salisbury, NC, US to St. Louis by bus
What is the distance between Salisbury and St. Louis?
The distance covered from Salisbury to St. Louis is 923 km (573 miles).
What are the departure and arrival locations for buses traveling from Salisbury to St. Louis?
Buses traveling this route start their trip at La Alcancia - Salisbury, in Salisbury, and end it at Gateway Station, in St. Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on Nov 22, 2025 with a price of $230To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to St. Louis, as early as possible.
You can expect to pay from $230 to $259 for a bus ticket from Salisbury, NC, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $259 which is on 2025-11-25.
What's the cheapest way to go from Salisbury, NC, US to St. Louis?
The bus is the cheapest travel choice for this destination
