Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 8:25 PM EST.
Compare 2 ways to go from Salisbury to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 23 hours 5 minutes, and with fares starting at just $178, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and St. Louis?
Compare bus companies
Based on 87403 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $188
Frequently asked questions about travelling from Salisbury, NC, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Salisbury to St. Louis?
The cheapest bus tickets from Salisbury to St. Louis start from $178. The average price for this route is around $232. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Salisbury to St. Louis?
The average bus travel time from Salisbury to St. Louis is 23h 5m, covering a distance of 926 km. The quickest bus can get you there in 21h 50m and is operated by Greyhound.
Which bus companies service the Salisbury to St. Louis route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Salisbury to St. Louis?
The earliest bus departs from Salisbury to St. Louis at 6:15am. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Salisbury to St. Louis?
A bus trip from Salisbury to St. Louis generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on Dec 3, 2025 with a price of $185To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to St. Louis, as early as possible.
You can expect to pay from $185 to $389 for a bus ticket from Salisbury, NC, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $185 which is on 2025-12-03.
What's the cheapest way to go from Salisbury, NC, US to St. Louis?
The bus is the cheapest travel choice for this destination
