Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Roanoke Bus Stop | Harrisburg Bus Station | CheapestFastest |
Last refresh of the prices: Today at 3:39 AM EST.
Compare 2 ways to go from Roanoke to Harrisburg
Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 9 hours 20 minutes, and with fares starting at just $129, it presents an excellent value for a comfortable ride.
Where are the popular stops in Roanoke and Harrisburg?
Stops in Roanoke
- AExit 140 (Park and Ride), Virginia 24153, USA
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Compare bus companies
Based on 87449 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $129
Frequently asked questions about travelling from Roanoke to Harrisburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Roanoke to Harrisburg?
The cheapest bus tickets from Roanoke to Harrisburg start from $129. The average price for this route is around $191. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Roanoke to Harrisburg?
The average bus travel time from Roanoke to Harrisburg is 9h 20m, covering a distance of 426 km. The quickest bus can get you there in 9h 20m and is operated by Greyhound.
Which bus companies service the Roanoke to Harrisburg route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Roanoke to Harrisburg?
The earliest bus departs from Roanoke to Harrisburg at 4:35am. And the latest bus departs at 4:35am.
What are the CO₂ emissions for the bus trip from Roanoke to Harrisburg?
A bus trip from Roanoke to Harrisburg generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Roanoke to Harrisburg was searched and found on Dec 25, 2025 with a price of $143To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Harrisburg, as early as possible.
You can expect to pay from $143 to $219 for a bus ticket from Roanoke to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $143 which is on 2025-12-25.
What's the cheapest way to go from Roanoke to Harrisburg?
The bus is the cheapest travel choice for this destination
