Bus Tickets from Prague to Lyon

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TodayJul 28
from US$116
TomorrowJul 29
from US$82
WedJul 30
from US$78
ThuJul 31
from US$78
FriAug 1
SatAug 2
from US$78
SunAug 3
from US$90
MonAug 4
from US$94

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 29 at
    Departure city: Prague
    Departure location: PRG Airport
    Arrival time: July 30 at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 29 at
    Departure city: Prague
    Departure location: Prague (Na Knížecí)
    Arrival time: July 30 at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 29 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: July 29 at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 29 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: July 30 at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 29 at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: July 30 at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 5:23 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Prague to Lyon: Trip Overview

Average Ticket PriceUS$100
Average Bus Trip Duration19h 10m
Number of daily buses8
Earliest bus departure3:50am
Distance863 km
Latest bus departure11:00pm

Prague to Lyon Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Prague to Lyon.

We make sure you can find a bus service from Prague to Lyon from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Lyon from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Prague - Lyon

  1. What is the travel distance from Prague to Lyon?

    The distance covered from Prague to Lyon is 861 km (534 miles).

  2. What are the departure and arrival locations for buses traveling from Prague to Lyon?

    Buses traveling this route start their trip at Florenc, in Prague, and end it at Lyon Airport, in Lyon.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-26
US$85
07-27
US$72
Today
US$108
07-29
US$78
07-30
US$73
07-31
US$73
08-01
US$85
08-02
US$73
busbud logoThe cheapest trip from Prague to Lyon was searched and found on Jul 27, 2025 with a price of US$72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Lyon, as early as possible.

You can expect to pay from US$72 to US$192 for a bus ticket from Prague to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at US$73 which is on 2025-07-30.

Usually Flixbus (CZ) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Prague to Lyon but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Prague to Lyon, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Lyon.

Tune out to the fine sounds of your best music playlist on your bus trip from Prague to Lyon while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Prague by bus?

Bus from Prague to Lyon

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Popular bus departures from Prague

Popular bus departures to Prague

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