Bus Tickets from Philadelphia, PA to Charleston, SC, US

Next bus departures

Next departures for Philadelphia to Charleston on November 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
4565 Gaynor Ave, North CharlestonCheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
4565 Gaynor Ave, North CharlestonNo tags
Greyhound Lines, Inc.Bus
Schuylkill & Walnut
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Cherry Hill Mall
4565 Gaynor Ave, North CharlestonNo tags
Greyhound Lines, Inc.Bus
Camden (Walter Rand Transportation Center)
4565 Gaynor Ave, North CharlestonNo tags

Last refresh of the prices: Today at 12:44 AM EST.

Compare 2 ways to go from Philadelphia to Charleston

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 12 hours, and with fares starting at just $134, it presents an excellent value for a comfortable ride.

2train per day
12hAverage Duration
898 kmDistance
82kgCO₂ emissions
Bus
Average Price$121 - $418Average Duration22h 20m
22kg CO₂e
Train
Average Price$134 - $420Average Duration12h
82kg CO₂e

Frequently asked questions about travelling from Philadelphia, PA to Charleston, SC, US by bus

  1. What is the distance between Philadelphia and Charleston?

    The distance covered from Philadelphia to Charleston is 906 km (562 miles).

  2. What are the departure and arrival locations for buses traveling from Philadelphia to Charleston?

    Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Charleston Bus Station, in Charleston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-19
$205
11-20
$262
Today
$226
11-22
$234
11-23
$214
11-24
$271
11-25
$387
11-26
$313
busbud logoThe cheapest trip from Philadelphia, PA to Charleston, SC, US was searched and found on Nov 19, 2025 with a price of $205

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Charleston, SC, US, as early as possible.

You can expect to pay from $205 to $495 for a bus ticket from Philadelphia, PA to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $214 which is on 2025-11-23.

What's the cheapest way to go from Philadelphia, PA to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

People from around the world trust Busbud

‌