Bus from Myrtle Beach to Spartanburg: Tickets & Schedules

Previously seen trips

Next departures for Myrtle Beach to Spartanburg on November 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Bus Station
SpartanburgNo tags
GreyhoundBus
Bus Station
SpartanburgNo tags
GreyhoundBus
Bus Station
SpartanburgNo tags
GreyhoundBus
Bus Station
SpartanburgNo tags
GreyhoundBus
Bus Station
SpartanburgNo tags

Get from Myrtle Beach to Spartanburg

This route is served by bus only

The journey takes about 16 hours 20 minutes, and with fares starting at just $86, it presents an excellent value for a comfortable ride.

1bus per day
16h 20mAverage Duration
322 kmDistance
8kgCO₂ emissions

Frequently asked questions about travelling from Myrtle Beach to Spartanburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Myrtle Beach to Spartanburg?

    The cheapest bus tickets from Myrtle Beach to Spartanburg start from $86. The average price for this route is around $86. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Myrtle Beach to Spartanburg?

    The average bus travel time from Myrtle Beach to Spartanburg is 16h 20m, covering a distance of 322 km. The quickest bus can get you there in 16h 20m and is operated by Greyhound.

  3. Which bus companies service the Myrtle Beach to Spartanburg route?

    Several major bus companies operate on this route with 1 buses available per day.

  4. What are the earliest and latest departure times for the bus from Myrtle Beach to Spartanburg?

    The earliest bus departs from Myrtle Beach to Spartanburg at 12:45pm. And the latest bus departs at 1:55pm.

  5. What are the CO₂ emissions for the bus trip from Myrtle Beach to Spartanburg?

    A bus trip from Myrtle Beach to Spartanburg generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-27
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11-28
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Today
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11-30
$264
12-01
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12-02
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12-03
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12-04
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busbud logoThe cheapest trip from Myrtle Beach to Spartanburg was searched and found on Nov 30, 2025 with a price of $264

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Spartanburg, as early as possible.

You can expect to pay from $264 to $264 for a bus ticket from Myrtle Beach to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at $264 which is on 2025-11-30.

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