Bus from Milwaukee to La Crosse, WI: Tickets & Schedules
Next bus departures
Next departures for Milwaukee to La Crosse on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse WI - University of Wisconsin (LSW)
CheapestFastest
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse St Andrew St
No tags
Next departures for Milwaukee to La Crosse on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
St. Paul & N5th
632 17th Street North
CheapestFastest
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse WI - University of Wisconsin (LSW)
No tags
Bus
St. Paul & N5th
La Crosse MTU Transit Center
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse St Andrew St
No tags
Next departures for Milwaukee to La Crosse on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
St. Paul & N5th
632 17th Street North
CheapestFastest
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse WI - University of Wisconsin (LSW)
No tags
Bus
St. Paul & N5th
La Crosse MTU Transit Center
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse St Andrew St
No tags
Next departures for Milwaukee to La Crosse on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
St. Paul & N5th
632 17th Street North
CheapestFastest
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse WI - University of Wisconsin (LSW)
No tags
Bus
St. Paul & N5th
La Crosse MTU Transit Center
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse St Andrew St
No tags
Next departures for Milwaukee to La Crosse on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
St. Paul & N5th
632 17th Street North
CheapestFastest
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse WI - University of Wisconsin (LSW)
No tags
Bus
St. Paul & N5th
La Crosse MTU Transit Center
No tags
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse St Andrew St
No tags
Next departures for Milwaukee to La Crosse on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse WI - University of Wisconsin (LSW)
CheapestFastest
Bus
Milwaukee Bus Station, St. Paul & N6th road.
La Crosse St Andrew St
No tags
Last refresh of the prices: Today at 12:22 AM CST.
Compare 2 ways to go from Milwaukee to La Crosse
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach La Crosse. The journey takes about 4 hours 45 minutes, and with fares starting at just $58, it presents an excellent value for a comfortable ride.
Based on 412 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the cleanliness but often complained with the WiFi. Megabus ticket prices on this trip start at $65
Based on 759 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the seats but often complained with the WiFi. Jefferson Lines ticket prices on this trip start at $58
Jefferson Lines Milwaukee La Crosse recent customer reviews
Frequently asked questions about travelling from Milwaukee to La Crosse, WI by bus
What is the distance between Milwaukee and La Crosse?
The distance between Milwaukee and La Crosse is around 284 km (176 miles).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-24
$62
11-25
$57
Today
$62
11-27
$62
11-28
$62
11-29
$62
11-30
$62
12-01
$62
The cheapest trip from Milwaukee to La Crosse, WI was searched and found on Nov 25, 2025 with a price of $57
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to La Crosse, WI, as early as possible.
You can expect to pay from $57 to $78 for a bus ticket from Milwaukee to La Crosse, WI based on the last 2 days. You can expect to find the cheapest price for the trip at $62 which is on 2025-11-27.
What's the cheapest way to go from Milwaukee to La Crosse, WI?
The bus is the cheapest travel choice for this destination
The cheapest trip from Milwaukee to La Crosse, WI was searched and found on Nov 25, 2025 with a price of $57
The bus is the cheapest travel choice for this destination
