Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tufesa | Santa Ana Col Del Rio | Cheapest | ||||
 | Bus | Mexicali - Stop | Santa Ana (Paso) - Stop | Fastest | ||||
| Bus | Mexicali - Stop | Santa Ana (Paso) - Stop | No tags | ||||
| Bus | Tufesa | Santa Ana Col Del Rio | No tags | ||||
| Bus | Mexicali - Stop | Santa Ana (Paso) - Stop | No tags |
Last refresh of the prices: Yesterday at 10:03 PM PST.
Compare 2 ways to go from Mexicali to Santa Ana
Among the sustainable travel choices, the bus stands out as a good way to reach Santa Ana. The journey takes about 7 hours 16 minutes, and with fares starting at just $85, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$85 - $98 | Average Duration7h 16m | 12kg CO₂e | ||
Carpool | Average Price$60 - $60 | Average Duration8h 20m | 20kg CO₂e |
Where are the popular stops in Mexicali and Santa Ana?
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
Stops in Santa Ana
- A
Parada de Autobuses de Santa Ana
Avenida Aldama # 301 entre Cerna y Guerrero - Colonia Centro, 84600 Santa Ana
Compare bus companies
Frequently asked questions about travelling from Mexicali to Santa Ana, SON, MX by bus
How far is Mexicali from Santa Ana?
The distance between Mexicali and Santa Ana is around 472 km (293 miles).
What are the departure and arrival locations for buses traveling from Mexicali to Santa Ana?
Buses traveling this route start their trip at Terminal de Autobuses de Mexicali, in Mexicali, and end it at Parada de Autobuses de Santa Ana, in Santa Ana.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexicali to Santa Ana, SON, MX was searched and found on Nov 25, 2025 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Santa Ana, SON, MX, as early as possible.
You can expect to pay from $79 to $86 for a bus ticket from Mexicali to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-11-25.
Top travelled bus routes
People from around the world trust Busbud
Popular bus departures from Mexicali
- Find bus tickets from Mexicali to Ensenada
- Mexicali to Tijuana bus times and fares
- How to travel from Mexicali to Los Mochis
- Find bus tickets from Mexicali to Mazatlán
- Mexicali to Puerto Peñasco bus times and fares
- How to travel from Mexicali to Hermosillo
- Find bus tickets from Mexicali to San José del Cabo