Cheap buses leaving Saturday
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: June 28 atDeparture city: MesaDeparture location: Mesa Bus StopArrival time: June 29 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Yesterday at 1:32 AM MST.
Prices and availability are subject to change.
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Bus Mesa to San Diego: Trip Overview
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Mesa to San Diego Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mesa to San Diego.
We make it our job to connect you with the most dependable bus companies that cover bus service from Mesa to San Diego.
Whether it is cheap bus tickets or more luxurious buses going to San Diego from Mesa, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Mesa and San Diego?
Frequently asked questions on the trip Mesa - San Diego, CA, US
What is the distance between Mesa and San Diego?
Mesa and San Diego are 502 km (312 miles) apart.
What are the departure and arrival locations for buses traveling from Mesa to San Diego?
Buses departing from Mesa Bus Station in Mesa will take you to Mission Valley Sheraton in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to San Diego was searched and found on Jun 28, 2025 with a price of US$77To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to San Diego, as early as possible.
You can expect to pay from US$77 to US$152 for a bus ticket from Mesa to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$77 which is on 2025-06-28.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mesa to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Mesa to San Diego.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mesa to San Diego.
Tune out to the fine sounds of your best music playlist on your bus trip from Mesa to San Diego while indulging in miles on end of beautiful scenic views.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
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