Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Louisville, KY | Lafayette Bus Stop | Cheapest | ||||
 | Bus | Louisville, KY | Lafayette Bus Stop | Fastest | ||||
| Bus | Louisville, KY | Lafayette Bus Stop | No tags |
Last refresh of the prices: Yesterday at 3:48 PM EST.
Get from Louisville to Lafayette
The journey takes about 4 hours 10 minutes, and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Where are the popular stops in Louisville and Lafayette?
Stops in Louisville
- A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Stops in Lafayette
- A
CityBus Center
N 3rd St & North St (Corner), Lafayette, IN 47901
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Frequently asked questions about travelling from Louisville to Lafayette, IN by bus
How far is Louisville from Lafayette?
Louisville and Lafayette are 258 km (160 miles) apart.
What are the departure and arrival locations for buses traveling from Louisville to Lafayette?
Buses departing from Louisville Greyhound Bus Station in Louisville will take you to CityBus Center in Lafayette.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Louisville to Lafayette, IN was searched and found on Nov 28, 2025 with a price of $53To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Lafayette, IN, as early as possible.
You can expect to pay from $53 to $132 for a bus ticket from Louisville to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-11-28.
