How far is Knoxville from Orlando?

The distance between Knoxville and Orlando is around 861 km (534 miles).

What are the departure and arrival locations for buses traveling from Knoxville to Orlando?

Buses traveling this route start their trip at 100 Kirkwood St, in Knoxville, and end it at Orlando Bus Station, in Orlando.

Bus Knoxville to Orlando from $138 | Refundable Tickets

Next bus departures

Next departures for Knoxville to Orlando on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	No tags

Next departures for Knoxville to Orlando on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	No tags

Next departures for Knoxville to Orlando on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	Cheapest
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	Fastest

Next departures for Knoxville to Orlando on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	No tags

Next departures for Knoxville to Orlando on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	Cheapest
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	Fastest

Next departures for Knoxville to Orlando on November 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	No tags

Next departures for Knoxville to Orlando on December 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	7:05pm	Knoxville Bus Station	19h 50m	2:55pm	The Florida Mall	Cheapest
	Bus	7:05pm	Knoxville Bus Station	13h 40m	8:45am	Orlando Bus Station	Fastest

Last refresh of the prices: Yesterday at 10:50 PM EST.

Get from Knoxville to Orlando

This route is served by bus only

The journey takes about 19 hours 30 minutes, and with fares starting at just $92, it presents an excellent value for a comfortable ride.

2bus per day

19h 30mAverage Duration

872 kmDistance

22kgCO₂ emissions

Where are the popular stops in Knoxville and Orlando?

Stops in Knoxville

A
100 Kirkwood St
Knoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Visit page

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $92

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Knoxville, TN to Orlando by bus

How far is Knoxville from Orlando?
The distance between Knoxville and Orlando is around 861 km (534 miles).
What are the departure and arrival locations for buses traveling from Knoxville to Orlando?
Buses traveling this route start their trip at 100 Kirkwood St, in Knoxville, and end it at Orlando Bus Station, in Orlando.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

$301

11-23

$224

Today

$300

11-25

$399

11-26

$349

11-27

$235

11-28

$235

11-29

$373

The cheapest trip from Knoxville, TN to Orlando was searched and found on Nov 23, 2025 with a price of $224

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Orlando, as early as possible.

You can expect to pay from $224 to $399 for a bus ticket from Knoxville, TN to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $235 which is on 2025-11-27.