Bus Tickets from Key West to Orlando

Next bus departures

Next departures for Key West to Orlando on November 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Key West Bus Station
Orlando Bus StationCheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Key West Bus Station
Orlando Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Key West Bus Station
The Florida MallNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Key West Bus Station
The Florida MallNo tags

Last refresh of the prices: Last Wednesday at 9:16 PM EST.

Get from Key West to Orlando

This route is served by bus only

The journey takes about 10 hours 40 minutes, and with fares starting at just $53, it presents an excellent value for a comfortable ride.

5bus per day
10h 40mAverage Duration
446 kmDistance
11kgCO₂ emissions

Frequently asked questions about travelling from Key West to Orlando by bus

  1. How far is Key West from Orlando?

    The distance covered from Key West to Orlando is 445 km (276 miles).

  2. What are the departure and arrival locations for buses traveling from Key West to Orlando?

    Buses traveling this route start their trip at Caroline St, in Key West, and end it at Orlando Bus Station, in Orlando.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-19
$101
11-20
$112
Today
$112
11-22
No data
11-23
No data
11-24
$102
11-25
$105
11-26
$107
busbud logoThe cheapest trip from Key West to Orlando was searched and found on Nov 19, 2025 with a price of $101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key West to Orlando, as early as possible.

You can expect to pay from $101 to $112 for a bus ticket from Key West to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-11-24.

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