Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Jacksonville Bus Station | Panama City Beach Station | Cheapest | ||||
| Bus | Jacksonville Bus Station | Panama City Beach Station | Fastest |
Last refresh of the prices: 2025-11-19 EST.
Get from Jacksonville to Panama City
The journey takes about 6 hours 20 minutes, and with fares starting at just $65, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jacksonville and Panama City?
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Compare bus companies
Frequently asked questions about travelling from Jacksonville, FL to Panama City, US by bus
How far is Jacksonville from Panama City?
It's about 387 km (240 miles) from Jacksonville to Panama City.
What are the departure and arrival locations for buses traveling from Jacksonville to Panama City?
Buses traveling this route start their trip at Jacksonville Amtrak Station, in Jacksonville, and end it at Panama City Greyhound Bus Station, in Panama City.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Panama City, US was searched and found on Nov 24, 2025 with a price of $65To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Panama City, US, as early as possible.
You can expect to pay from $65 to $175 for a bus ticket from Jacksonville, FL to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-11-27.
