Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Tornado Bus + Expreso | Bus | Houston Airline | Williston Rd & I-75 | Cheapest | ||||
 | Bus | Houston Lockwood, (TX - TBC Lockwood) | Williston Rd & I-75 | Fastest | ||||
 | Bus | Houston Bus Station | Gainesville Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | Rosa Parks Station | No tags | ||||
| Bus | Houston Airline | Williston Rd & I-75 | No tags |
Last refresh of the prices: Today at 2:18 PM CST.
Get from Houston to Gainesville
The journey takes about 23 hours 35 minutes, and with fares starting at just $145, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Houston and Gainesville?
Frequently asked questions about travelling from Houston, US to Gainesville, FL by bus
What is the distance between Houston and Gainesville?
It's about 1261 km (782 miles) from Houston to Gainesville.
What are the departure and arrival locations for buses traveling from Houston to Gainesville?
Buses traveling this route start their trip at Hillcroft Ave & Southwest Freeway, in Houston, and end it at Williston Rd & I-75, in Gainesville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Gainesville, FL was searched and found on Nov 17, 2025 with a price of $225To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Gainesville, FL, as early as possible.
You can expect to pay from $225 to $317 for a bus ticket from Houston, US to Gainesville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $253 which is on 2025-11-20.
