Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Houston Southwest, (TX - EEX Houston Southwest) | Williston Rd & I-75 | Cheapest | ||||
| Bus | Houston Lockwood, (TX - TBC Lockwood) | Williston Rd & I-75 | Fastest | ||||
 | Bus | Houston Bus Station | Gainesville Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | Rosa Parks Station | No tags | ||||
| Bus | Houston Southwest, (TX - EEX Houston Southwest) | Williston Rd & I-75 | No tags |
Last refresh of the prices: Today at 09:21 CST.
Get from Houston to Gainesville
The journey takes about 23 hours 35 minutes, and with fares starting at just £79, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and Gainesville?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in Gainesville
- A3509 SW Williston Rd, Gainesville, FL 32608, USA
- B700 SE 3rd St, Gainesville, FL 32601
- C101 NE 23rd Ave, Gainesville, FL 32609
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Frequently asked questions about travelling by bus from Houston, US to Gainesville, FL
What's the distance between Houston and Gainesville by coach?
The distance between Houston and Gainesville by coach is approximately 782 miles (1261 km).
What is the best way to go from Houston to Gainesville without flying?
You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Gainesville, FL was searched and found on 18 Nov 2025 with a price of £138To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Gainesville, FL as early as possible.
You can expect to pay from £138 to £173 for a bus ticket from Houston, US to Gainesville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at £145, which is on 2025-11-21.
