How much is the bus ticket from Harrisburg to Syracuse?

The cheapest bus tickets from Harrisburg to Syracuse start from $109. The average price for this route is around $190. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Harrisburg to Syracuse?

The average bus travel time from Harrisburg to Syracuse is 11h, covering a distance of 319 km. The quickest bus can get you there in 8h 5m and is operated by FlixBus .

Which bus companies service the Harrisburg to Syracuse route?

Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from Harrisburg to Syracuse?

The earliest bus departs from Harrisburg to Syracuse at 12:20am. And the latest bus departs at 11:20pm.

What are the CO₂ emissions for the bus trip from Harrisburg to Syracuse?

A bus trip from Harrisburg to Syracuse generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Harrisburg to Syracuse?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Harrisburg to Syracuse?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Harrisburg to Syracuse?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Harrisburg to Syracuse?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Harrisburg to Syracuse from $99 | Refundable Tickets

Next bus departures

Next departures for Harrisburg to Syracuse on December 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:20am	Harrisburg Bus Station	11h	11:20am	Syracuse (Regional Transportation Center)	Cheapest
	Bus	9:10pm	Harrisburg Bus Station	9h	6:10am	Syracuse (Regional Transportation Center)	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	5:40am	Harrisburg Bus Station	9h 35m	3:15pm	Syracuse (Regional Transportation Center)	No tags
	Bus	10:25am	Harrisburg Bus Station	12h 15m	10:40pm	Syracuse (Regional Transportation Center)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:30pm	Harrisburg Bus Station	10h 45m	1:15am	Syracuse (Regional Transportation Center)	No tags

Last refresh of the prices: Last Saturday at 1:20 PM EST.

Get from Harrisburg to Syracuse

This route is served by bus only

The journey takes about 11 hours, and with fares starting at just $109, it presents an excellent value for a comfortable ride.

6bus per day

11hAverage Duration

319 kmDistance

8kgCO₂ emissions

Where are the popular stops in Harrisburg and Syracuse?

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

Greyhound

3.5/587,451 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,735 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Harrisburg to Syracuse, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Harrisburg to Syracuse?
The cheapest bus tickets from Harrisburg to Syracuse start from $109. The average price for this route is around $190. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Syracuse?
The average bus travel time from Harrisburg to Syracuse is 11h, covering a distance of 319 km. The quickest bus can get you there in 8h 5m and is operated by FlixBus.
Which bus companies service the Harrisburg to Syracuse route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Harrisburg to Syracuse?
The earliest bus departs from Harrisburg to Syracuse at 12:20am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Syracuse?
A bus trip from Harrisburg to Syracuse generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Harrisburg to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Harrisburg to Syracuse?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Harrisburg to Syracuse?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to Syracuse?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-23

$177

12-24

$166

Today

No data

12-26

$166

12-27

No data

12-28

No data

12-29

No data

12-30

No data

The cheapest trip from Harrisburg to Syracuse, US was searched and found on Dec 24, 2025 with a price of $166

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Syracuse, US, as early as possible.

You can expect to pay from $166 to $279 for a bus ticket from Harrisburg to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $166 which is on 2025-12-26.