Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Harrisburg Bus Station | Syracuse (Regional Transportation Center) | Cheapest | ||||
| Bus | Harrisburg Bus Station | Syracuse (Regional Transportation Center) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Harrisburg Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Harrisburg Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Harrisburg Bus Station | Syracuse (Regional Transportation Center) | No tags |
Last refresh of the prices: Last Saturday at 13:20 EST.
Get from Harrisburg to Syracuse
The journey takes about 11 hours, and with fares starting at just £59, it presents an excellent value for a comfortable ride.
Where are the popular stops in Harrisburg and Syracuse?
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
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Frequently asked questions about travelling by bus from Harrisburg to Syracuse, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Harrisburg to Syracuse?
The cheapest coach tickets from Harrisburg to Syracuse start from £59. The average price for this route is around £103. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Harrisburg to Syracuse?
The average bus journey time from Harrisburg to Syracuse is 11h, covering a distance of 198 miles. The fastest bus can take you there in 8h 5m and is operated by FlixBus.
Which bus companies service the Harrisburg to Syracuse route?
What is the earliest and latest departure time for the bus from Harrisburg to Syracuse?
The earliest bus departs from Harrisburg to Syracuse at 00:20. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Harrisburg to Syracuse?
A bus journey from Harrisburg to Syracuse produces an estimated 8 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Harrisburg to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which company has the best Wi-Fi from Harrisburg to Syracuse?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Harrisburg to Syracuse?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to Syracuse?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Syracuse, US was searched and found on 24 Dec 2025 with a price of £90To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Syracuse, US as early as possible.
You can expect to pay from £90 to £152 for a bus ticket from Harrisburg to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at £90, which is on 2025-12-26.
