How much is the bus ticket from Greenville to Boston?

The cheapest bus tickets from Greenville to Boston start from $139. The average price for this route is around $288. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Greenville to Boston?

The average bus travel time from Greenville to Boston is 22h 55m, covering a distance of 1280 km. The quickest bus can get you there in 20h 55m and is operated by FlixBus .

Which bus companies service the Greenville to Boston route?

Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus , Greyhound .

What are the earliest and latest departure times for the bus from Greenville to Boston?

The earliest bus departs from Greenville to Boston at 7:25am. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Greenville to Boston?

A bus trip from Greenville to Boston generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Greenville to Boston?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11648 reviews.

Which bus company has the best Wi-Fi from Greenville to Boston?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Greenville to Boston?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Greenville to Boston?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Greenville to Boston from $129 | Refundable Tickets

Next bus departures

Next departures for Greenville to Boston on December 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:05pm	1116 Woodruff Rd	21h 20m	9:25am	Boston (South Station)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	20h 50m	6:50pm	Boston (South Station)	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	22h 55m	3:10pm	Boston (South Station)	No tags
	Bus	12:05pm	1116 Woodruff Rd	20h 55m	9:00am	Brookline	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	1d 7h	5:40am	Brookline	No tags

Next departures for Greenville to Boston on December 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:05pm	1116 Woodruff Rd	1d 2h	2:45pm	151 Steel Pl, Cambridge	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	20h 50m	6:50pm	Boston (South Station)	Fastest
	Bus	7:25am	1116 Woodruff Rd	21h 45m	5:10am	Boston (South Station)	No tags
	Bus	12:05pm	1116 Woodruff Rd	21h 20m	9:25am	Boston (South Station)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	22h 55m	3:10pm	Boston (South Station)	No tags

Next departures for Greenville to Boston on December 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25am	1116 Woodruff Rd	21h 45m	5:10am	Boston (South Station)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	20h 50m	6:50pm	Boston (South Station)	Fastest
	Bus	12:05pm	1116 Woodruff Rd	21h 20m	9:25am	Boston (South Station)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	22h 55m	3:10pm	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25am	1116 Woodruff Rd	22h 15m	5:40am	Brookline	No tags

Next departures for Greenville to Boston on December 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:05pm	1116 Woodruff Rd	1d 2h	2:45pm	151 Steel Pl, Cambridge	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	20h 50m	6:50pm	Boston (South Station)	Fastest
	Bus	7:25am	1116 Woodruff Rd	21h 45m	5:10am	Boston (South Station)	No tags
	Bus	12:05pm	1116 Woodruff Rd	21h 20m	9:25am	Boston (South Station)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	22h 55m	3:10pm	Boston (South Station)	No tags

Next departures for Greenville to Boston on December 31
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:00pm	1116 Woodruff Rd	23h 45m	9:45pm	151 Steel Pl, Cambridge	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	20h 50m	6:50pm	Boston (South Station)	Fastest
	Bus	7:25am	1116 Woodruff Rd	21h 45m	5:10am	Boston (South Station)	No tags
	Bus	12:05pm	1116 Woodruff Rd	21h 20m	9:25am	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25am	1116 Woodruff Rd	23h 55m	7:20am	Brookline	No tags

Next departures for Greenville to Boston on January 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:05pm	1116 Woodruff Rd	1d 2h	2:45pm	151 Steel Pl, Cambridge	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	20h 50m	6:50pm	Boston (South Station)	Fastest
	Bus	7:25am	1116 Woodruff Rd	21h 45m	5:10am	Boston (South Station)	No tags
	Bus	12:05pm	1116 Woodruff Rd	21h 20m	9:25am	Boston (South Station)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	22h 55m	3:10pm	Boston (South Station)	No tags

Last refresh of the prices: Last Tuesday at 10:34 PM EST.

Compare 2 ways to go from Greenville to Boston

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 22 hours 55 minutes, and with fares starting at just $139, it presents an excellent value for a comfortable ride.

9bus per day

22h 55mAverage Duration

1280 kmDistance

32kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$139 - $707	Average Duration22h 55m	CO₂ emissions 32kg CO₂e
Train	Average Price$276 - $2,685	Average Duration20h 44m	CO₂ emissions 116kg CO₂e

Where are the popular stops in Greenville and Boston?

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Compare bus companies

FlixBus

3.5/511,741 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,452 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Greenville, SC to Boston, MA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Greenville to Boston?
The cheapest bus tickets from Greenville to Boston start from $139. The average price for this route is around $288. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Boston?
The average bus travel time from Greenville to Boston is 22h 55m, covering a distance of 1280 km. The quickest bus can get you there in 20h 55m and is operated by FlixBus.
Which bus companies service the Greenville to Boston route?
Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Greyhound.
What are the earliest and latest departure times for the bus from Greenville to Boston?
The earliest bus departs from Greenville to Boston at 7:25am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Boston?
A bus trip from Greenville to Boston generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Boston?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11648 reviews.
Which bus company has the best Wi-Fi from Greenville to Boston?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Greenville to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-24

$298

12-25

$292

Today

$264

12-27

$275

12-28

$368

12-29

$318

12-30

$279

12-31

$247

The cheapest trip from Greenville, SC to Boston, MA, US was searched and found on Dec 31, 2025 with a price of $247

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Boston, MA, US, as early as possible.

You can expect to pay from $247 to $393 for a bus ticket from Greenville, SC to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $247 which is on 2025-12-31.

Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.