Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | 1116 Woodruff Rd | Boston (South Station) | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Boston (South Station) | Fastest | ||||
 | Bus | 1116 Woodruff Rd | Boston (South Station) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | 1116 Woodruff Rd | Brookline | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Brookline | No tags |
Last refresh of the prices: Last Friday at 16:46 EST.
Compare 2 ways to travel from Greenville to Boston
Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 22 hours 55 minutes and with fares starting at just £89, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Boston?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Frequently asked questions about travelling by bus from Greenville, SC to Boston, MA, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Greenville to Boston?
The cheapest coach tickets from Greenville to Boston start from £89. The average price for this route is around £152. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Greenville to Boston?
The average bus journey time from Greenville to Boston is 22h 55m, covering a distance of 794 miles. The fastest bus can take you there in 20h 45m and is operated by FlixBus.
Which bus companies service the Greenville to Boston route?
What is the earliest and latest departure time for the bus from Greenville to Boston?
The earliest bus departs from Greenville to Boston at 07:25. And the latest bus departs at 22:00.
What are the CO₂ emissions for the bus trip from Greenville to Boston?
A bus journey from Greenville to Boston produces an estimated 32 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Greenville to Boston?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11799 reviews.
Which company has the best Wi-Fi from Greenville to Boston?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Greenville to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Boston, MA, US was searched and found on 6 Jan 2026 with a price of £120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Boston, MA, US as early as possible.
You can expect to pay from £120 to £194 for a bus ticket from Greenville, SC to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £122, which is on 2026-01-08.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Greenville, SC to Boston, MA, US?
The bus is the cheapest travel choice for this destination
