Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | DENVER | Gateway Station | CheapestFastest |
Last refresh of the prices: Today at 5:08 AM MST.
Compare 2 ways to go from Denver to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 16 hours 30 minutes, and with fares starting at just $123, it presents an excellent value for a comfortable ride.
Where are the popular stops in Denver and St. Louis?
Stops in Denver
- A1701 Wynkoop St, Denver, CO 80202
- B
Bus Station
1055 19th St, Denver, CO 80202
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Frequently asked questions about travelling from Denver to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Denver to St. Louis?
The cheapest bus tickets from Denver to St. Louis start from $123. The average price for this route is around $196. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Denver to St. Louis?
The average bus travel time from Denver to St. Louis is 16h 30m, covering a distance of 1280 km. The quickest bus can get you there in 16h 30m and is operated by Greyhound.
Which bus companies service the Denver to St. Louis route?
Several major bus companies operate on this route with 1 buses available per day, including services from Greyhound, Burlington Trailways.
What are the earliest and latest departure times for the bus from Denver to St. Louis?
The earliest bus departs from Denver to St. Louis at 7:00pm. And the latest bus departs at 8:10pm.
What are the CO₂ emissions for the bus trip from Denver to St. Louis?
A bus trip from Denver to St. Louis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Denver to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Denver to St. Louis?
Based on Busbud reviews, the bus company Burlington Trailways has the highest Wi-Fi rating with a score of 5.0.
Which bus company has the best on-time performance from Denver to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Denver to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Denver to St. Louis was searched and found on Dec 1, 2025 with a price of $134To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to St. Louis, as early as possible.
You can expect to pay from $134 to $441 for a bus ticket from Denver to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $134 which is on 2025-12-01.
What's the cheapest way to go from Denver to St. Louis?
The bus is the cheapest travel choice for this destination
