What is the travel distance from Chicago to Jefferson City?

The distance between Chicago and Jefferson City is approximately 531 km (329 miles).

Bus Chicago to Jefferson City from $88 | Refundable Tickets

Next bus departures

Next departures for Chicago to Jefferson City on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	CheapestFastest
Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags

Next departures for Chicago to Jefferson City on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	12:40am	Chicago 95Th & Dan Ryan	15h 20m	4:00pm	Jefferson City	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15am	Downtown Greyhound Station	15h 45m	4:00pm	Jefferson City	No tags
	Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
	Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags
	Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	No tags

Next departures for Chicago to Jefferson City on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	12:40am	Chicago 95Th & Dan Ryan	15h 20m	4:00pm	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15am	Downtown Greyhound Station	15h 45m	4:00pm	Jefferson City	No tags
	Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
	Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags

Next departures for Chicago to Jefferson City on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	12:40am	Chicago 95Th & Dan Ryan	15h 20m	4:00pm	Jefferson City	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15am	Downtown Greyhound Station	15h 45m	4:00pm	Jefferson City	No tags
	Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
	Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags
	Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	No tags

Next departures for Chicago to Jefferson City on November 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	12:40am	Chicago 95Th & Dan Ryan	15h 20m	4:00pm	Jefferson City	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15am	Downtown Greyhound Station	15h 45m	4:00pm	Jefferson City	No tags
	Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
	Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags
	Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	No tags

Next departures for Chicago to Jefferson City on December 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	12:40am	Chicago 95Th & Dan Ryan	15h 20m	4:00pm	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15am	Downtown Greyhound Station	15h 45m	4:00pm	Jefferson City	No tags
	Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
	Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags

Next departures for Chicago to Jefferson City on December 2
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:30pm	Chicago 95Th & Dan Ryan	17h 30m	4:00pm	Jefferson City	CheapestFastest
Bus	9:40pm	Downtown Greyhound Station	18h 20m	4:00pm	Jefferson City	No tags
Bus	10:00pm	537-517 W. Jackson Blvd	18h	4:00pm	Jefferson City	No tags

Last refresh of the prices: Last Monday at 7:38 PM CST.

Compare 2 ways to go from Chicago to Jefferson City

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Jefferson City. The journey takes about 7 hours 46 minutes, and with fares starting at just $71, it presents an excellent value for a comfortable ride.

2train per day

7h 46mAverage Duration

532 kmDistance

48kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$73 - $233	Average Duration16h 50m	CO₂ emissions 13kg CO₂e
Train	Average Price$71 - $263	Average Duration7h 46m	CO₂ emissions 48kg CO₂e

Compare bus companies

Greyhound

3.5/587,396 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,446 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Chicago to Jefferson City, MO by bus

What is the travel distance from Chicago to Jefferson City?
The distance between Chicago and Jefferson City is approximately 531 km (329 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-24

$185

11-25

$192

Today

$181

11-27

$129

11-28

$146

11-29

$238

11-30

$286

12-01

$164

The cheapest trip from Chicago to Jefferson City, MO was searched and found on Nov 27, 2025 with a price of $129

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Jefferson City, MO, as early as possible.

You can expect to pay from $129 to $292 for a bus ticket from Chicago to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $129 which is on 2025-11-27.