How much is the bus ticket from Chicago to Jefferson City?

The cheapest coach tickets from Chicago to Jefferson City start from £40. The average price for this route is around £53. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Chicago to Jefferson City?

The average bus journey time from Chicago to Jefferson City is 16h 20m, covering a distance of 324 miles. The fastest bus can take you there in 15h 15m and is operated by Greyhound .

Which bus companies service the Chicago to Jefferson City route?

Several major bus companies operate on this route with 5 buses available per day.

What is the earliest and latest departure time for the bus from Chicago to Jefferson City?

The earliest bus departs from Chicago to Jefferson City at 00:15. And the latest bus departs at 23:45.

What are the CO₂ emissions for the bus trip from Chicago to Jefferson City?

A bus journey from Chicago to Jefferson City produces an estimated 13 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Bus Chicago to Jefferson City from £42 | Refundable Tickets

Next bus departures

Next departures from Chicago to Jefferson City on 4 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	CheapestFastest
Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	No tags
Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 5 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	No tags
	Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 6 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	No tags
	Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 7 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	No tags
	Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 8 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags
	Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 9 February
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	No tags
	Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 10 February
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	22:50	Downtown Greyhound Station	17h 10m	16:00	Jefferson City	Cheapest
Bus	23:40	Chicago 95Th & Dan Ryan	16h 20m	16:00	Jefferson City	Fastest
Bus	23:10	537-517 W. Jackson Blvd	16h 50m	16:00	Jefferson City	No tags

Last refresh of the prices: Yesterday at 00:34 CST.

Compare 2 ways to travel from Chicago to Jefferson City

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Jefferson City. The journey takes about 7 hours 46 minutes and with fares starting at just £37, it presents an excellent value for a comfortable ride.

2train per day

7h 46mAverage duration

330 milesDistance

48kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£40 - £101	Average duration16h 20m	CO₂ emissions 13kg CO₂e
Train	Average price£37 - £98	Average duration7h 46m	CO₂ emissions 48kg CO₂e

Compare bus companies

Greyhound

3.5/587,519 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wi‑Fi2.5

Based on 87519 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at £40

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from Chicago to Jefferson City, MO

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Chicago to Jefferson City?
The cheapest coach tickets from Chicago to Jefferson City start from £40. The average price for this route is around £53. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Chicago to Jefferson City?
The average bus journey time from Chicago to Jefferson City is 16h 20m, covering a distance of 324 miles. The fastest bus can take you there in 15h 15m and is operated by Greyhound.
Which bus companies service the Chicago to Jefferson City route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Chicago to Jefferson City?
The earliest bus departs from Chicago to Jefferson City at 00:15. And the latest bus departs at 23:45.
What are the CO₂ emissions for the bus trip from Chicago to Jefferson City?
A bus journey from Chicago to Jefferson City produces an estimated 13 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

02/02

£104

03/02

£84

Today

£88

05/02

£64

06/02

£57

07/02

£80

08/02

£60

09/02

£49

The cheapest trip from Chicago to Jefferson City, MO was searched and found on 9 Feb 2026 with a price of £49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Jefferson City, MO as early as possible.

You can expect to pay from £49 to £120 for a bus ticket from Chicago to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at £49, which is on 2026-02-09.