Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | City of Portland | Cheapest | ||||
 | Bus | Niagara Frontier Transportation Authority | City of Portland | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Buffalo (BUF) Airport | City of Portland | No tags |
Last refresh of the prices: Last Thursday at 8:42 PM EST.
Get from Buffalo to Portland
The journey takes about 20 hours 51 minutes, and with fares starting at just $160, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Portland?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Portland
- A
Greyhound Station Portland Maine
389 Congress St, Portland, ME 04102, USA
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Frequently asked questions about travelling from Buffalo, NY to Portland, ME by bus
What is the travel distance from Buffalo to Portland?
The distance covered from Buffalo to Portland is 704 km (437 miles).
What are the departure and arrival locations for buses traveling from Buffalo to Portland?
Buses traveling this route start their trip at Buffalo Airport, in Buffalo, and end it at Greyhound Station Portland Maine, in Portland.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Portland, ME was searched and found on Nov 27, 2025 with a price of $217To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Portland, ME, as early as possible.
You can expect to pay from $217 to $217 for a bus ticket from Buffalo, NY to Portland, ME based on the last 2 days. You can expect to find the cheapest price for the trip at $217 which is on 2025-11-27.
