How much does a train ticket from Salisbury to St. Louis cost?

The average train ticket price from Salisbury to St. Louis is $427. The best way to find train tickets from Salisbury to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the train trip from Salisbury to St. Louis?

A train trip between Salisbury and St. Louis is around 1d 13h, although the fastest train will take about 1d 13h. This is the time it takes to travel the 573 miles that separates the two cities.

How many daily trains are there between Salisbury and St. Louis?

The number of trains from Salisbury to St. Louis can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Salisbury to St. Louis by comparing and selecting the train that fits you travel style and budget on Busbud.

Which train companies travel from Salisbury to St. Louis?

When taking the train from Salisbury to St. Louis, you can travel comfortably and safely with Amtrak.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can explore the city. The top sights and things to do are Anheuser-Busch Brewery, Forest Park, Old St. Louis County Courthouse, Saint Louis Zoo, Gateway Arch.

Train Salisbury to St. Louis from $2,223 | Refundable Tickets

Next train departures

Next departures for Salisbury to St. Louis on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	6:17am	Salisbury, NC	1d 13h	7:07pm	Gateway Station	CheapestFastest

Last refresh of the prices: Last Wednesday at 11:07 PM EST.

Compare 2 ways to go from Salisbury to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 23 hours 5 minutes and with fares starting at just $124, it presents an excellent value for a comfortable ride.

2bus per day

23h 5mAverage Duration

574 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$124 - $208	Average Duration23h 5m	CO₂ emissions 23kg CO₂e
Train	Average Price$324 - $2,303	Average Duration1d 13h	CO₂ emissions 84kg CO₂e

Train Companies

Amtrak

4/55,606 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5606 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $324

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Salisbury, NC, US to St. Louis by train

How much does a train ticket from Salisbury to St. Louis cost?
How long is the train trip from Salisbury to St. Louis?
How many daily trains are there between Salisbury and St. Louis?
Which train companies travel from Salisbury to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

No data

11/23

$1,928

Today

No data

11/25

$2,223

11/26

No data

11/27

No data

11/28

No data

11/29

No data

The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on Nov 23, 2025 with a price of $1,928

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Salisbury, NC, US to St. Louis, as early as possible.

You can expect to pay from $1,928 to $2,223 for a train ticket from Salisbury, NC, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $2,223 which is on 2025-11-25.