Train tickets from Philadelphia, PA to Greenville, SC

Previously seen trips

Next departures for Philadelphia to Greenville on November 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
30th Street Station
Greenville StationNo tags
AmtrakTrain
30th Street Station
Greenville StationNo tags
AmtrakTrain
30th Street Station
Greenville StationNo tags
AmtrakTrain
30th Street Station
Greenville StationNo tags
AmtrakTrain
30th Street Station
Greenville StationNo tags

Compare 2 ways to go from Philadelphia to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 18 hours 35 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.

19bus per day
18h 35mAverage Duration
532 milesDistance
21kgCO₂ emissions
Average Price$77 - $279Average Duration18h 35m
21kg CO₂e
Average Price$128 - $269Average Duration13h 46m
78kg CO₂e

Frequently asked questions about traveling from Philadelphia, PA to Greenville, SC by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/21
$312
11/22
$214
Today
$150
11/24
$150
11/25
$179
11/26
$179
11/27
$122
11/28
No data
busbud logoThe cheapest trip from Philadelphia, PA to Greenville, SC was searched and found on Nov 27, 2025 with a price of $122

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Philadelphia, PA to Greenville, SC, as early as possible.

You can expect to pay from $122 to $757 for a train ticket from Philadelphia, PA to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $122 which is on 2025-11-27.

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