Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Jacksonville Amtrak Station | Florence Station | CheapestFastest | |||||
| Jacksonville Amtrak Station | Florence Station | No tags | |||||
| Jacksonville Amtrak Station | Florence Station | No tags |
Last refresh of the prices: Yesterday at 8:25 AM EST.
Accepted payments
Compare 2 ways to go from Jacksonville to Florence
Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 7 hours and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Train Jacksonville, FL to Florence, SC, US: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5563 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $52
Jacksonville to Florence Train
With Busbud, comparing and booking tickets for a train from Jacksonville to Florence is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
Train service from Jacksonville to Florence will be provided by the most trusted companies.
Whether it is train tickets or first class train tickets going to Florence from Jacksonville, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Jacksonville, FL - Florence, SC, US
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on Nov 1, 2025 with a price of $49To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville, FL to Florence, SC, US, as early as possible.
You can expect to pay from $49 to $387 for a train ticket from Jacksonville, FL to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-08.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Jacksonville to Florence is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
No matter if you plan to take a regional or high-speed train to Florence, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
By choosing the train between Jacksonville and Florence, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Jacksonville to Florence.
Did you know?
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Top Traveled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Trains Connecting Jacksonville
Trains Leaving from Jacksonville
Popular Trains Connecting Florence
Trains Going to Florence
Popular train trips
Top Routes Worldwide
- Train from Wells to Fargo
- Train from Columbia to New York City
- Train from Detroit to Red Wing
- Train from Holland to Taylor
- Train from Los Angeles to Glendale
- Train from Waterloo to Buffalo
- Train from Niagara Falls to Ontario
- Train from Washington to Leavenworth
- Train from Washington to Everett
- Train from Buffalo to New York City
- Train from Seattle to Washington
- Train from Rochester to New York City
- Train from Vancouver to Washington
- Train from Ventura to Simi Valley
- Train from Newark to Essex